Recombinant Mouse Gfra1 Protein, Myc/DDK-tagged

• Cat.No.: Gfra1-3197M
• Product Overview: Purified recombinant protein of mouse full-length glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a transmembrane protein that functions as the receptor for glial cell line derived neurotrophic factor (GDNF). The encoded protein undergoes proteolytic processing to generate a glycosylphosphatidylinositol-anchored cell surface coreceptor that forms a complex with the Ret tyrosine kinase in GDNF signaling pathway. Mice lacking the encoded protein exhibit deficits in the kidneys, the enteric nervous system, and spinal motor and sensory neurons similar mice deficient in GDNF or Ret.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 51.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 [ Mus musculus (house mouse) ]
• Official Symbol: Gfra1
• Synonyms: Gfra1; glial cell line derived neurotrophic factor family receptor alpha 1; GDNFR; AU042498; GDNF family receptor alpha-1; GDNFR-alpha-1; GFR alpha-1; TGF-beta-related neurotrophic factor receptor 1
• Gene ID: 14585
• mRNA Refseq: NM_010279
• Protein Refseq: NP_034409
• UniProt ID: P97785