Recombinant Mouse Gfral protein, His-Avi-tagged

• Cat.No.: Gfral-060M
• Product Overview: Recombinant Mouse GFRAL Protein is expressed from Expi293 with a His Tag and Avi Tag at the N-terminal. It contains Gln20-Glu350.

Specification

• Description: GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
• Source: HEK293
• Species: Mouse
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 40.1 kDa.Due to glycosylation, the protein migrates to 48-60 Kda based on Bis-Tris PAGE result.
• Protein length: Gln20-Glu350
• Endotoxin: Less than 1 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: Gfral
• Official Symbol: Gfral
• Synonyms: GFR alpha like; GFR alpha-like; GFRAL; GRAL; GDNF family receptor alpha-lik; C6orf144
• Gene ID: 404194
• mRNA Refseq: NM_205844.3
• Protein Refseq: NP_995316.2
• UniProt ID: Q6SJE0