Recombinant Mouse Gfral protein, His-Avi-tagged


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Recombinant Mouse Gfral protein, His-Avi-tagged

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Cat.No. : Gfral-060M
Product Overview : Recombinant Mouse GFRAL Protein is expressed from Expi293 with a His Tag and Avi Tag at the N-terminal. It contains Gln20-Glu350.
Description : GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
Source : HEK293
Species : Mouse
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 40.1 kDa.Due to glycosylation, the protein migrates to 48-60 Kda based on Bis-Tris PAGE result.
Protein length : Gln20-Glu350
Endotoxin : Less than 1 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Tris-Bis PAGE of Gfral-060M :

SEC-HPLC of Gfral-060M :

Gene Name : Gfral
Official Symbol : Gfral
Synonyms : GFR alpha like; GFR alpha-like; GFRAL; GRAL; GDNF family receptor alpha-lik; C6orf144
Gene ID : 404194
mRNA Refseq : NM_205844.3
Protein Refseq : NP_995316.2
UniProt ID : Q6SJE0
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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