Recombinant Mouse Icam1 protein, His-tagged
Cat.No. : | Icam1-2778M |
Product Overview : | Recombinant Mouse Icam1 aa. (Val46~Leu301 (Accession # P13597)) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1. It participates in the innate immune response. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 36kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Val46~Leu301 (Accession # P13597) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 4.8. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : | Reconstitute in sterile ddH2O. |
Gene Name : | Icam1 intercellular adhesion molecule 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Icam1 |
Synonyms : | CD54; Ly-47; Icam-1; MALA-2; myD10; intercellular adhesion molecule 1 |
Gene ID : | 15894 |
mRNA Refseq : | NM_010493.3 |
Protein Refseq : | NP_034623.1 |
UniProt ID : | P13597 |
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◆ Lysates | ||
ICAM1-1970RCL | Recombinant Rat ICAM1 cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (5)
Ask a questionYes, targeting ICAM1 is being explored as a potential therapeutic strategy for inflammatory diseases, with research focusing on developing ICAM1 inhibitors.
ICAM1 is upregulated during inflammation, promoting the adhesion of immune cells to the endothelium and facilitating their migration into inflamed tissues.
ICAM1 expression can be altered in cancer cells and is implicated in promoting cancer progression by facilitating tumor cell adhesion, invasion, and metastasis.
ICAM1 levels can be measured in blood or tissue samples, and elevated levels may serve as diagnostic markers for certain inflammatory diseases.
Elevated levels of ICAM1 in some diseases may serve as prognostic markers, indicating disease severity and potential outcomes.
Customer Reviews (3)
Write a reviewManufacturers may provide documentation of the protein's validation, which includes information about its purity, concentration, stability, and potential contaminants.
This can be particularly important in clinical trials to ensure accurate and reliable results.
If the need arises for larger quantities of ICAM1 protein during the later stages of clinical trials, the manufacturer can facilitate scale-up production processes to meet those requirements.
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