Recombinant Mouse IL-22

• Cat.No.: IL22-90M
• Product Overview: Mouse IL-22 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Species: Mouse
• Source: Yeast
• Tag: Non
• Description: IL-22 is a member of the IL-10 family, which includes IL-19, IL-20, IL-24, and IL-26. This family represents a class of potent mediators of cellular inflammatory responses. IL-22 shares use of IL-10R2 in cell signaling with other members of this family. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens, especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 is rapidly produced by a subset of splenic cells and can also be produced by Th17 cells. IL-22 likely plays a role in the coordinated response of both adaptive and innate immune systems.
• Form: Lyophilized
• Molecular Mass: 16.7 kDa
• AA Sequence: LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV NAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV (146)
• Applications: The mouse IL-22 protein can be used in cell culture, as an IL-22 ELISA Standard, and as a Western Blot Control.
• Storage: -20 C

Gene Information

• Gene Name: Il22 interleukin 22 [ Mus musculus ]
• Official Symbol: IL22
• Synonyms: IL22; interleukin 22; interleukin-22; ILTIF alpha; IL-TIF alpha; interleukin-22a; IL-10-related T-cell-derived-inducible factor; interleukin 10-related T cell-derived inducible factor; IL-22; Iltif; IL-22a; ILTIFa; MGC129416; MGC129417
• Gene ID: 50929
• mRNA Refseq: NM_016971
• Protein Refseq: NP_058667
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem
• Function: cytokine activity; protein binding