Recombinant Mouse Il11ra1, His tagged

Cat.No. : Il11ra1-2294M
Product Overview : Recombinant Mouse Il11ra1 extracellular domain (NP_001156873.1) (Met 1-Gln 367), fused with a C-terminal polyhistidine tag, was produced in Human Cell.
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Source : Human Cells
Species : Mouse
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The secreted recombinant mouse IL11Rα consists of 355 amino acids and has a calculated molecular mass of 39.2 kDa. As a result of glycosylation, the apparent molecular mass of rmIL11Rα is approximately 45-50 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4oC before opening to recover the entire contents.
Gene Name : Il11ra1 interleukin 11 receptor, alpha chain 1 [ Mus musculus ]
Official Symbol : Il11ra1
Gene ID : 16157
mRNA Refseq : NM_001163401
Protein Refseq : NP_001156873

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What are the advanced imaging techniques used to visualize the dynamic conformational changes of IL11RA1 upon ligand binding? 07/04/2022

Advanced imaging techniques visualize IL11RA1 conformational changes upon ligand binding.

Can you elaborate on the utilization of animal models and transgenic approaches to study the tissue-specific functions of IL11RA1? 04/15/2022

Animal models and transgenics study IL11RA1's tissue-specific functions.

How do reporter gene assays help in studying the transcriptional regulation of IL11RA1 gene expression? 02/28/2022

Reporter gene assays study IL11RA1 gene expression regulation.

Can you explain the role of high-throughput screening in identifying small molecules that modulate IL11RA1 activity? 10/02/2021

High-throughput screening identifies small molecules modulating IL11RA1 activity.

What insights have functional genomics studies provided regarding the role of IL11RA1 in disease pathogenesis? 09/22/2020

Functional genomics unveil IL11RA1's role in disease pathogenesis.

How does site-directed mutagenesis contribute to understanding the binding interface between IL11RA1 and IL11? 07/09/2020

Site-directed mutagenesis reveals the binding interface of IL11RA1 and IL11.

What methodologies like fluorescence resonance energy transfer (FRET) elucidate the intracellular signaling pathways activated by IL11RA1? 01/07/2020

Fluorescence resonance energy transfer (FRET) reveals IL11RA1 signaling pathways.

How are biophysical methods such as circular dichroism (CD) spectroscopy employed to investigate the secondary structure changes of IL11RA1? 01/26/2019

Circular dichroism (CD) spectroscopy probes IL11RA1 secondary structure changes.

How do proteomic analyses contribute to identifying IL11RA1-interacting proteins and potential signaling complexes? 09/18/2018

Proteomics identifies IL11RA1-interacting proteins and signaling complexes.

What strategies like surface plasmon resonance (SPR) aid in quantifying the binding kinetics between IL11RA1 and its downstream effectors? 01/02/2017

Surface plasmon resonance (SPR) quantifies IL11RA1 binding kinetics.

Customer Reviews (3)

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Reviews
08/14/2021

    Good for cytokine assays.

    02/01/2021

      Effective in signaling studies.

      01/09/2019

        Consistent bioactivity.

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