Recombinant Mouse Il17f Protein Il17f-143M

Recombinant Mouse Il17f Protein

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Recombinant Mouse Il17f Protein

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Cat.No. : Il17f-143M
Product Overview : Purified recombinant protein of Mouse interleukin 17F (Il17f) (Arg29-Ala161) without tag was expressed in E.coli.
Description : Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover. Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis. Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.
Source : E. coli
Species : Mouse
Bio-activity : The ED50 is 300 to 600 ng/ml, corresponding to a specific activity of 0.16 - 0.33 x 10^4 units/mg, determined by a dose dependent stimulation of fetal mouse skin fibroblasts production of CXCL1.
Molecular Mass : 15 kDa
Endotoxin : Less than 0.01 ng per µg protein as determined by the LAL method
Purity : >98%, as determined by Coomassie stained SDS-PAGE.
Stability : Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 ug/mL in specified buffer
Storage Buffer : 10 mM NaH2PO4, 0.15 M NaCl, pH7.2
Gene Name : Il17f interleukin 17F [ Mus musculus (house mouse) ]
Official Symbol : Il17f
Synonyms : Il17f; interleukin 17F; C87042; IL-17F; interleukin-17F
Gene ID : 257630
mRNA Refseq : NM_145856
Protein Refseq : NP_665855
UniProt ID : Q7TNI7

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