Il17rd-3502M
Optional Service: Optional requirements on this protein
Product Overview :
Purified recombinant protein of mouse full-length interleukin 17 receptor D (Il17rd), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description :
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK. Mediates JNK activation and may be involved in apoptosis. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Might have a role in the early stages of fate specification of GnRH-secreting neurons. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Source :
HEK293T
Species :
Mouse
Tag :
Myc/DDK
Molecular Mass :
82.3 kDa
Purity :
> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage :
Store at -80 centigrade after receiving vials.
Concentration :
>50 μg/mL as determined by microplate BCA method
Storage Buffer :
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.