Recombinant Mouse Il18 Protein, His tagged

• Cat.No.: Il18-31M
• Product Overview: Recombinant Mouse Il18 Protein, Sourced from E.coli, Asn36-Ser192, with N-terminal His Tag.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 36-192 aa
• Description: Interleukin-18 (IL-18) is a proinflammatory cytokine that is produced by many cell types including macrophages, dendtritic cells, microglial cells, and keratinocytes. It is a member of the IL-1 family of cytokines and functions with IL-12 to induce production of IFNg from T cells and NK cells. Uncontrolled release of IL-18 is associated with severe chronic inflammatory diseases. IL-18 is synthesized as an inactive precursor protein that is processed by caspase-1 into its mature secretable form.
• Form: Lyophilized from 1× PBS with Trehalose
• Molecular Mass: 20.2 kDa
• Purity: >95% by SDS-PAGE
• Applications: ELISA and Western Blot Analysis
• Storage: 2 years at -20 to -80 centigrade as supplied. Upon reconstitution: 2 years at -80 centigrade; 2 years at -20 centigrade For long-term storage, store for up to 2 years at -20 & -80 centigrade after reconstitution. Expiration is 2 years from date of receipt.
• Shipping: Ambient
• Reconstitution: Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% protein.

Gene Information

• Gene Name: Il18 interleukin 18 [ Mus musculus (house mouse) ]
• Official Symbol: Il18
• Synonyms: IL18; interleukin 18; interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Igif; Il-18
• Gene ID: 16173
• mRNA Refseq: NM_008360
• Protein Refseq: NP_032386
• UniProt ID: P70380

Q&As

What are the difference between IL18-01HG, IL18-153HG and IL18-500H. (sequence, biological activity, QC, or what do you propose to buy)

IL18-01HG: Sequence: a.a.37-193 Endotoxin: <20 EU/mg Bio-activity: >5.0 x 10^4 IU/mg QC: Activity test, SDS-PAGE, LAL, SEC-HPLC IL18-153HG: Protein length: Tyr37-Asp193 AA Sequence: YFGKLESKLS VIRNLNDQVL FIDQGNRPLF EDMTDSDCRD NAPRTIFIISMYKDSQPRGM AVTISVKCEK ISTLSCENKI ISFKEMNPPD NIKDTKSDIIFFQRSVPGHD NKMQFESSSY EGYFLACEKE RDLFKLILKK EDELGDRSIMFTVQNEDVD Bio-activity: 1.0*10^6IU Measured by its ability to induce IFN-gamma secretion by KG‐1 human acute myelogenous leukemia cells in the presence of TNF-alpha. QC: Activity test, SDS-PAGE, LAL IL18-500H Recombinant Human IL18 will be custom produced upon order. All the sequence, purity, activity, and QC procedures will be optional and decided by our customer.