Recombinant Mouse Il19 Protein, His-tagged
Cat.No. : | Il19-1015M |
Product Overview : | Recombinant Mouse Il19 Protein (Leu25-Ala176) with His tag was expressed in 293F. |
- Specification
- Gene Information
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Description : | Predicted to enable cytokine activity. Involved in negative regulation of low-density lipoprotein particle clearance. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway; positive regulation of intrinsic apoptotic signaling pathway; and reactive oxygen species metabolic process. Predicted to be located in extracellular space. Orthologous to human IL19 (interleukin 19). |
Source : | HEK293F |
Species : | Mouse |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 19.2 kDa; Accurate Molecular Mass: 26-38 kDa |
Protein length : | Leu25-Ala176 |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | Il19 interleukin 19 [ Mus musculus (house mouse) ] |
Official Symbol : | Il19 |
Synonyms : | IL19; interleukin 19; interleukin-19; IL-19; |
Gene ID : | 329244 |
mRNA Refseq : | NM_001009940 |
Protein Refseq : | NP_001009940 |
UniProt ID : | Q8CJ70 |
Products Types
◆ Recombinant Protein | ||
IL19-4438H | Recombinant Human IL19 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il19-157M | Recombinant Active Mouse IL19 Protein, His-tagged(C-ter) | +Inquiry |
Il19-367I | Active Recombinant Mouse Il19 Protein (153 aa) | +Inquiry |
IL19-146H | Recombinant Human IL19 Protein | +Inquiry |
Il19-150M | Active Recombinant Mouse Il19 Protein (Leu25-Ala176), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
IL19-5242HCL | Recombinant Human IL19 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionConfocal microscopy and flow cytometry visualize IL19-induced cellular responses and track receptor internalization upon ligand binding.
Functional assays using immune cell cultures and cytokine profiling assays dissect IL19's impact on immune cell polarization and cytokine secretion.
Biophysical techniques like surface plasmon resonance and analytical ultracentrifugation quantify IL19's binding to IL20RA and IL20RB and reveal receptor complex composition.
Biophysical techniques such as surface plasmon resonance and isothermal titration calorimetry quantify IL19's binding kinetics to its receptor complexes.
CRISPR/Cas9 knockout models and siRNA-mediated knockdown in specific cell types unravel IL19's cell-specific roles.
Neutralizing antibodies, receptor blockade experiments, and in vivo disease models evaluate IL19's suitability as a therapeutic target in inflammatory and autoimmune diseases.
Recombinant protein expression in bacterial or mammalian systems followed by purification allows generation of functional IL19 for various experimental assays.
Reporter gene assays, ChIP, and DNA-protein interaction studies probe IL19's transcriptional regulation and interactions with specific DNA sequences.
Animal models and patient samples, combined with histopathology and molecular assays, shed light on IL19's involvement in skin disorders and its therapeutic potential.
Animal wound healing models, in vitro cell migration assays, and co-culture experiments investigate IL19's role in tissue repair and its effects on fibroblast and keratinocyte function.
Customer Reviews (3)
Write a reviewHigh reproducibility.
Suitable for Western blot.
Effective in cell differentiation.
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