- Mouse(3)
Recombinant Mouse Il1f5 Protein
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Cat.No. : | Il1f5-148M |
Product Overview : | Purified recombinant protein of Mouse interleukin 1 family, member 5 (delta) (Il1f5), transcript variant 2 without tag was expressed in E.coli. |
Description : | Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | Measured by its ability to inhibit IL-36γ induced IL-6 production by human PBMCs. |
Molecular Mass : | 17 kDa |
AA Sequence : | VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Purity : | >95%, as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. |
Storage Buffer : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2 |
Reconstitution : | Resuspend the protein in the desired concentration in proper buffer. |
Figure : |
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Gene Name : | Il1f5 interleukin 1 family, member 5 (delta) [ Mus musculus (house mouse) ] |
Official Symbol : | Il1f5 |
Synonyms : | Il1f5; interleukin 1 family, member 5 (delta); IL36RN; Il-1h3; Il1hy1; IL-36Ra; AI413231; Fil1delta; interleukin-36 receptor antagonist protein; IL-1 delta; IL-1F5; IL-1HY1; IL-1L1; interleukin 1 receptor antagonist homolog 1; interleukin-1 HY1; interleukin-1 delta; interleukin-1 family member 5; interleukin-1 homolog 3; interleukin-1-like protein 1 |
Gene ID : | 54450 |
mRNA Refseq : | NM_019451 |
Protein Refseq : | NP_062324 |
UniProt ID : | Q9QYY1 |
◆ Recombinant Protein
Il1f5-553M | Recombinant Mouse Il1f5 protein | +Inquiry |
Il1f5-2836M | Recombinant Mouse Il1f5 protein, His & T7-tagged | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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