| Description : |
Enables cytokine activity and interleukin-2 receptor binding activity. Involved in negative regulation of T-helper 17 cell differentiation. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of macromolecule metabolic process; and regulation of lymphocyte activation. Located in extracellular space. Is expressed in liver; omental bursa; thymus; and thymus primordium. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in several diseases, including Takayasu's arteritis; auditory system disease (multiple); autoimmune disease (multiple); carcinoma (multiple); and neurodegenerative disease (multiple). Orthologous to human IL2 (interleukin 2). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
N-His-Avi |
| Protein length : |
Ala21-Gln169 |
| Conjugation/Label : |
Biotin |
| Form : |
Lyophilised |
| Endotoxin : |
Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). |
| Notes : |
FOR RESEARCH USE ONLY (RUO). |
| Storage : |
The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade. |
| Storage Buffer : |
Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM |
