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Recombinant Mouse IL2RB Protein, His-tagged

Cat.No. : IL2RB-1257M
Product Overview : Recombinant Mouse IL2RB Protein (27-240aa) was expressed in Yeast with N-terminal His-tag.
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  • Gene Information
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Description : The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other cytokine receptors.
Source : Yeast
Species : Mouse
Tag : His
Form : Tris-based buffer, 50% glycerol.
Molecular Mass : 27.0 kDa
AA Sequence : AVKNCSHLECFYNSRANVSCMWSHE EALNVTTCHVHAKSNLRHWNKTCEL TLVRQASWACNLILGSFPES
QSLTSVDLLDINVVCWEEKGWRRVK TCDFHPFDNLRLVAPHSLQVLHIDT QRCNISWKVSQVSHYIEPYL
EFEARRRLLGHSWEDASVLSLKQRQ QWLFLEMLIPSTSYEVQVRVKAQRN NTGTWSPWSQPLTFRTRPAD
PMKE
Purity : Greater than 90% as determined by SDS-PAGE.
Storage : The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Gene Name : Il2rb interleukin 2 receptor, beta chain [ Mus musculus (house mouse) ]
Official Symbol : IL2RB
Synonyms : p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta
Gene ID : 16185
mRNA Refseq : NM_008368.4
Protein Refseq : NP_032394.1
UniProt ID : P16297

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is IL2RB and what are its clinical applications? 09/18/2022

It is an artificial protein prepared by genetic engineering techniques that can mimic the natural IL-2R beta subunit and is used to explore how to treat cancer and autoimmune diseases by regulating the IL-2 signaling pathway.

What is the effect of IL2RB in the treatment of tumor? 05/27/2022

There has shown good therapeutic effect in the treatment of some tumors (such as lung cancer, melanoma, etc.), but the specific efficacy varies with the patient's condition, treatment timing and other factors.

What is the therapeutic mechanism of IL2RB in clinical use? 12/13/2021

This protein can simulate the natural IL-2R beta subunit and participate in the IL-2 signaling pathway, thereby enhancing the body's immunity.

What diseases is IL2RB associated with? 06/07/2021

IL2RB is associated with a variety of cancers (such as gastric cancer, lung cancer, liver cancer, lymphoma, etc.) and autoimmune diseases (such as rheumatoid arthritis, systemic lupus erythematosus, etc.).

Can IL2RB be an alternative to traditional treatment? 04/10/2020

IL2RB can be used as a new therapeutic method, but it does not mean that it can replace traditional therapeutic methods. In the course of specific treatment, different treatment methods should be considered according to the condition.

Does IL2RB have side effects? 06/22/2019

IL2RB may produce some side effects, including fever, headache, nausea, vomiting, etc., but the incidence of different side effects is low.

Customer Reviews (3)

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Reviews
09/07/2021

    Immunogenicity is very weak and does not cause an immune response.

    12/27/2019

      Detection method is very sensitive and can detect trace amounts of protein.

      08/15/2019

        Preparation process is very simple and can be easily prepared.

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