Recombinant Mouse Il34 Protein, Myc/DDK-tagged

• Cat.No.: Il34-3523M
• Product Overview: Purified recombinant protein of mouse full-length interleukin 34 (Il34), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 26.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Il34 interleukin 34 [ Mus musculus (house mouse) ]
• Official Symbol: Il34
• Synonyms: IL34; interleukin 34; interleukin-34; IL-34; AI593503; 2010004A03Rik
• Gene ID: 76527
• mRNA Refseq: NM_001135100
• Protein Refseq: NP_001128572
• UniProt ID: Q8R1R4