Recombinant Mouse IL-34
|Product Overview :||Mouse IL-34 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.|
- Gene Information
- Related Products
|Description :||Interleukin-34 (IL-34) is a homodimeric cytokine identified by high throughput screening of human recombinant secreted factors. It contains no known conserved domains and has no sequence homology with other cytokines. IL-34 is recognized by colony-stimulating factor 1 receptor (CSF-1R). CSF-1R also binds CSF-1, also called macrophage colony-stimulating factor (M-CSF). Both IL-34 and CSF-1 are involved in the survival, proliferation and differentiation of mononuclear phagocytes, including monocytes, macrophages, dendritic cells, Langerhans cells, microglia and osteoclasts.|
|Molecular Mass :||24.6 kDa|
|AA Sequence :||NENLEIWTLT QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL QKAHVSEREL RYLWVLVSLN ATESVMDVLL EGHPSWKYLQ EVQTLLENVQ RSLMDVEIGP HVEAVLSLLS TPGLSLKLVR PKALLDNCFR VMELLYCSCC KQSPILKWQD CELPRLHPHS PGSLMQCTAT NVYPLSRQTP TSLPGSPSSS HGSLP (215)|
|Applications :||The Mouse IL-34 protein can be used in cell culture, as an IL-34 ELISA Standard, and as a Western Blot Control.|
|Storage :||-20 C|
|Gene Name :||Il34 interleukin 34 [ Mus musculus ]|
|Official Symbol :||IL34|
|Synonyms :||IL34; interleukin 34; interleukin-34; IL-34; AI593503; 2010004A03Rik;|
|Gene ID :||76527|
|mRNA Refseq :||NM_001135100|
|Protein Refseq :||NP_001128572|
|Function :||cytokine activity; growth factor activity; macrophage colony-stimulating factor receptor binding; macrophage colony-stimulating factor receptor binding;|
|◆ Recombinant Protein|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
There are no clear studies showing the effect of IL34 on tumor prognosis.
Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.
May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.
No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.
Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.
The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.
Customer Reviews (3)Write a review
IL34 has shown good biocompatibility and safety in related experiments. -
When using IL34 for experiments, the experimental conditions and results are highly repeatable. -
Quality is stable and reliable, with no significant differences between batches. -
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