Recombinant Mouse IL-34

Cat.No. : IL34-81M
Product Overview : Mouse IL-34 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
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  • Gene Information
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Description : Interleukin-34 (IL-34) is a homodimeric cytokine identified by high throughput screening of human recombinant secreted factors. It contains no known conserved domains and has no sequence homology with other cytokines. IL-34 is recognized by colony-stimulating factor 1 receptor (CSF-1R). CSF-1R also binds CSF-1, also called macrophage colony-stimulating factor (M-CSF). Both IL-34 and CSF-1 are involved in the survival, proliferation and differentiation of mononuclear phagocytes, including monocytes, macrophages, dendritic cells, Langerhans cells, microglia and osteoclasts.
Source : Yeast
Species : Mouse
Form : Lyophilized
Molecular Mass : 24.6 kDa
AA Sequence : NENLEIWTLT QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL QKAHVSEREL RYLWVLVSLN ATESVMDVLL EGHPSWKYLQ EVQTLLENVQ RSLMDVEIGP HVEAVLSLLS TPGLSLKLVR PKALLDNCFR VMELLYCSCC KQSPILKWQD CELPRLHPHS PGSLMQCTAT NVYPLSRQTP TSLPGSPSSS HGSLP (215)
Applications : The Mouse IL-34 protein can be used in cell culture, as an IL-34 ELISA Standard, and as a Western Blot Control.
Storage : -20 C
Gene Name : Il34 interleukin 34 [ Mus musculus ]
Official Symbol : IL34
Synonyms : IL34; interleukin 34; interleukin-34; IL-34; AI593503; 2010004A03Rik;
Gene ID : 76527
mRNA Refseq : NM_001135100
Protein Refseq : NP_001128572
Function : cytokine activity; growth factor activity; macrophage colony-stimulating factor receptor binding; macrophage colony-stimulating factor receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the effect of IL34 on tumor prognosis? 09/19/2022

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments? 05/14/2022

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor? 07/09/2020

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing? 04/02/2020

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system? 03/26/2020

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34? 01/31/2019

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.

Customer Reviews (3)

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Reviews
05/10/2021

    IL34 has shown good biocompatibility and safety in related experiments. -

    01/19/2020

      When using IL34 for experiments, the experimental conditions and results are highly repeatable. -

      10/24/2019

        Quality is stable and reliable, with no significant differences between batches. -

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