Recombinant Mouse Il6 Protein Il6-113M

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Recombinant Mouse Il6 Protein

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Recombinant Mouse Il6 Protein

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Cat.No. :	Il6-113M
Product Overview :	Purified recombinant protein of Mouse interleukin 6 (Il6) without tag was expressed in E.coli.
Description :	This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source :	E. coli
Species :	Mouse
Bio-activity :	The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is< 0.02 ng/ml, corresponding to a specific activity of≥ 5 x 10^7 units/mg.
Molecular Mass :	21.7 kDa
AA Sequence :	MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
Endotoxin :	Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Purity :	>95%, as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Storage :	Store at -80 centigrade.
Storage Buffer :	Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Reconstitution :	Resuspend the protein in the desired concentration in proper buffer.
Figure :

Gene Name :	Il6 interleukin 6 [ Mus musculus (house mouse) ]
Official Symbol :	Il6
Synonyms :	Il6; interleukin 6; Il-6; interleukin-6; B-cell hybridoma growth factor; interleukin HP-1
Gene ID :	16193
mRNA Refseq :	NM_031168
Protein Refseq :	NP_112445
UniProt ID :	P08505

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