Recombinant Mouse Itgb4 Protein, Myc/DDK-tagged

• Cat.No.: Itgb4-3608M
• Product Overview: Purified recombinant protein of mouse full-length integrin beta 4 (Itgb4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 195.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Itgb4 integrin beta 4 [ Mus musculus (house mouse) ]
• Official Symbol: Itgb4
• Synonyms: ITGB4; integrin beta 4; integrin beta-4; CD104; AA407042; C230078O20
• Gene ID: 192897
• mRNA Refseq: NM_133663
• Protein Refseq: NP_598424
• UniProt ID: A2A864