Recombinant Mouse Itgb6 Protein, Myc/DDK-tagged

• Cat.No.: Itgb6-3610M
• Product Overview: Purified recombinant protein of mouse full-length integrin beta 6 (Itgb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 86.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Itgb6 integrin beta 6 [ Mus musculus (house mouse) ]
• Official Symbol: Itgb6
• Synonyms: ITGB6; integrin beta 6; integrin beta-6; 2210409C20Rik; 4831415H04Rik
• Gene ID: 16420
• mRNA Refseq: NM_001159564
• Protein Refseq: NP_001153036
• UniProt ID: Q9Z0T9