| Cat.No. : |
Pf4-4803M |
| Product Overview : |
Purified recombinant protein of Mouse platelet factor 4 (Pf4 / PF-4) without tag was expressed in E. coli. |
| Description : |
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation. |
| Source : |
E. coli |
| Species : |
Mouse |
| Bio-activity : |
The ED50 is 3-5 μg/ml, corresponding to a specific activity 2.0-3.3 × 10^2 units/mg, determined by a dose-dependent inhibition of human FGF-basic-dependent proliferation of human umbilical vein endothelial cells (HUVEC). |
| Molecular Mass : |
8.2 kDa |
| Protein length : |
Val30-Ser105 |
| Endotoxin : |
Less than 0.01 ng/μg protein as determined by the LAL method |
| Purity : |
> 98%, as determined by Coomassie stained SDS-PAGE. |
| Stability : |
Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. |
| Concentration : |
Protein formulated and vialed at >50 μg/mL in specified buffer |
| Storage Buffer : |
1 x PBS |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.