"Prdx6" Related Products


Recombinant Mouse Prdx6 protein, His/T7-tagged

Cat.No.: Prdx6-32M
Product Overview: Recombinant Mouse Prdx6(Met1~Pro224) fused with His/T7 tag at N-terminal was expressed in E. coli.
Description: This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane phospholipids and plays an important role in phospholipid homeostasis based on its ability to generate lysophospholipid substrate for the remodeling pathway of phospholipid synthesis. Mice lacking this gene are sensitive to oxidant stress, have altered lung phospholipid metabolism and susceptible to skin tumorigenesis. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 4.
Source: E. coli
Species: Mouse
Tag : His/T7
Form: pH7.4, 0.01% SKL, 1mM DTT, 5% Trehalose, Proclin300.
Molecular Mass: 28.7kDa
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: >95%
Applications: SDS-PAGE; WB; ELISA; IP
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: Prdx6 peroxiredoxin 6 [ Mus musculus ]
Official Symbol: Prdx6
Synonyms: PRDX6; peroxiredoxin 6; peroxiredoxin-6; 1-Cys Prx; 1-Cys peroxiredoxin; antioxidant protein 2; non-selenium glutathione peroxidase; peroxiredoxin 5, related sequence 3; peroxiredoxin 6, related sequence 3; anti-oxidant protein 2, related sequence 3; acidic calcium-independent phospholipase A2; GPx; Aop2; CC26; CP-3; Ltw4; NSGP; Ltw-4; NSGPx; ORF06; Prdx5; Brp-12; Lvtw-4; aiPLA2; 1-cysPrx; AA690119; Aop2-rs3; Prdx6-rs3; mKIAA0106; 9430088D19Rik; KIAA0106;
Gene ID: 11758
mRNA Refseq: NM_007453
Protein Refseq: NP_031479
UniProt ID: O08709
Chromosome Location: 1 H2.1; 1 69.75 cM
Pathway: Metabolic pathways, organism-specific biosystem; Phenylalanine metabolism, organism-specific biosystem; Phenylalanine metabolism, conserved biosystem; phosphate acquisition II, organism-specific biosystem;
Function: antioxidant activity; catalytic activity; glutathione peroxidase activity; hydrolase activity; oxidoreductase activity; peroxidase activity; peroxiredoxin activity; phospholipase A2 activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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