Recombinant Mouse Ror1 Protein, His-tagged

Cat.No. : Ror1-430M
Product Overview : Recombinant Mouse Ror1 protein with His tag was expressed in HEK293.
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Description : This gene encodes a receptor tyrosine kinase that has been implicated in nervous system development, specifically in the maintenance of neural progenitor cell fate, neurite extension and synapse formation. The encoded protein, likely a pseudokinase that lacks catalytic activity, may also regulate adipogenesis. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized
Molecular Mass : 42.6 kDa
Protein Length : 937
AA Sequence : MHRPRRRGTRPPPLALLAALLLAAR GADAQETELSVSAELVPTSSWNTSS EIDKGSYLTLDEPMNNITTSLGQTA ELHCKVSGNPPPSIRWFKNDAPVVQ EPRRISFRATNYGSRLRIRNLDTTD TGYFQCVATNGKKVVSTTGVLFVKF GPPPTASPGSSDEYEEDGFCQPYRG IACARFIGNRTVYMESLHMQGEIEN QITAAFTMIGTSSHLSDKCSQFAIP SLCHYAFPYCDETSSVPKPRDLCRD ECEVLENVLCQTEYIFARSNPMILM RLKLPNCEDLPQPESPEAANCIRIG IPMADPINKNHKCYNSTGVDYRGTV SVTKSGRQCQPWNSQYPHTHSFTAL RFPELNGGHSYCRNPGNQKEAPWCF TLDENFKSDLCDIPACDSKDSKEKN KMEILYILVPSVAIPLAIAFLFFFI CVCRNNQKSSSPPVQRQPKPVRGQN VEMSMLNAYKPKSKAKELPLSAVRF MEELGECTFGKIYKGHLYLPGMDHA QLVAIKTLKDYNNPQQWTEFQQEAS LMAELHHPNIVCLLGAVTQEQPVCM LFEYMNQGDLHEFLIMRSPHSDVGC SSDEDGTVKSSLDHGDFLHIAIQIA AGMEYLSSHFFVHKDLAARNILIGE QLHVKISDLGLSREIYSADYYRVQS KSSLPIRWMPPEAIMYGKFSSDSDI WSFGVVLWEIFSFGLQPYYGFSNQE VIEMVRKRQLLPCSEDCPPRMYSLM TECWNEIPSRRPRFKDIHVRLRSWE GLSSHTSSTTPSGGNATTQTTSLSA SPVSNLSNPRFPNYMFPSQGITPQG QIAGFIGPAIPQNQRFIPINGYPIP PGYAAFPAAHYQPAGPPRVIQHCPP PKSRSPSSASGSTSTGHVASLPSSG SNQEANVPLLPHMSIPNHPGGMGIT VFGNKSQKPYKIDSKQSSLLGDSHI HGHTESMISAEV
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : Ror1 receptor tyrosine kinase-like orphan receptor 1 [ Mus musculus (house mouse) ]
Official Symbol : Ror1
Synonyms : ROR1; receptor tyrosine kinase-like orphan receptor 1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor related 1; neurotrophic tyrosine kinase, receptor-related 1; mRor1; Ntrkr1; 2810404D04Rik;
Gene ID : 26563
mRNA Refseq : NM_013845
Protein Refseq : NP_038873
UniProt ID : Q9Z139

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (4)

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What is the expression level of ROR1 in normal tissues. 11/28/2022

ROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.

What are the effects of inhibiting ROR1 expression? 07/14/2022

Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.

What biological processes is ROR1 involved in? 12/26/2021

ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.

What diseases is ROR1 involved in? 03/01/2021

ROR1 is involved in the study of breast, lung and ovarian cancers.

Customer Reviews (3)

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Reviews
10/18/2022

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    08/13/2022

      Excellent after-sales service, solving many experimental problems.

      04/12/2021

        Fast and timely shipment helped me to get satisfactory experimental results in short time.

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