Recombinant Mouse Spsb2 Protein, MYC/DDK-tagged Spsb2-1060M

Recombinant Mouse Spsb2 Protein, MYC/DDK-tagged


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Recombinant Mouse Spsb2 Protein, MYC/DDK-tagged

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Cat.No. : Spsb2-1060M
Product Overview : Purified recombinant protein of full-length mouse splA/ryanodine receptor domain and SOCS box containing 2 (Spsb2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : This gene encodes a member of the SSB family of proteins that contain a central SPRY (repeats in splA and ryanodine receptors) domain and a C-terminal SOCS (suppressor of cytokine signaling) box. The encoded protein is an adaptor protein in the E3 ubiquitin ligase complex that ubiquitinates inducible nitric oxide synthase and targets it for proteasomal degradation. Mice lacking the encoded protein exhibit lower blood urea nitrogen levels and mild thrombocytopenia due to reduced platelet production. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293T
Species : Mouse
Molecular Mass : 28.9 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Spsb2 splA/ryanodine receptor domain and SOCS box containing 2 [ Mus musculus (house mouse) ]
Official Symbol : Spsb2
Synonyms : Spsb2; splA/ryanodine receptor domain and SOCS box containing 2; C9; SSB2; Grcc9; AI461677; SPRY domain-containing SOCS box protein 2; gene-rich cluster protein C9
Gene ID : 14794
mRNA Refseq : NM_013539
Protein Refseq : NP_038567
UniProt ID : O88838

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