Recombinant Rat F2r Protein, His-tagged

• Cat.No.: F2r-2176R
• Product Overview: Recombinant Rat F2r Protein (Ser46-Thr109) with a N-His tag was expressed in E. coli.

Specification

• Description: Predicted to enable several functions, including G-protein alpha-subunit binding activity; G-protein beta-subunit binding activity; and thrombin-activated receptor activity. Involved in several processes, including establishment of synaptic specificity at neuromuscular junction; positive regulation of cytosolic calcium ion concentration; and protein kinase C-activating G protein-coupled receptor signaling pathway. Located in neuromuscular junction and postsynaptic membrane. Used to study hypertension. Biomarker of brain edema and brain ischemia. Orthologous to human F2R (coagulation factor II thrombin receptor).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21 kDa
• Protein length: Ser46-Thr109
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: F2r coagulation factor II (thrombin) receptor [ Rattus norvegicus (Norway rat) ]
• Official Symbol: F2r
• Synonyms: F2r; coagulation factor II (thrombin) receptor; Par1; TRGPC; proteinase-activated receptor 1
  PAR-1
  Thrombin receptor
  coagulation factor II receptor
  protease-activated receptor 1
• Gene ID: 25439
• mRNA Refseq: NM_012950
• Protein Refseq: NP_037082
• UniProt ID: P26824