Recombinant Rat NFKBIA Protein
Cat.No. : | NFKBIA-3975R |
Product Overview : | Recombinant Rat NFKBIA full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [ Rattus norvegicus ] |
Official Symbol : | NFKBIA |
Gene ID : | 25493 |
mRNA Refseq : | NM_001105720.2 |
Protein Refseq : | NP_001099190.2 |
MIM : | |
UniProt ID : | Q63746 |
Products Types
◆ Recombinant Protein | ||
NFKBIA-3340H | Recombinant Human NFKBIA protein(Phe2-Leu317), His-tagged | +Inquiry |
NFKBIA-2835R | Recombinant Rhesus Macaque NFKBIA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFKBIA-819H | Recombinant Human NFKBIA Protein, MYC/DDK-tagged | +Inquiry |
NFKBIA-3634R | Recombinant Rat NFKBIA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFKBIA-6039M | Recombinant Mouse NFKBIA Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NFKBIA-437HCL | Recombinant Human NFKBIA lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (6)
Ask a questionThe interaction between NFKBIA protein and NF-κB can be identified by co-immunoprecipitation, bimolecular fluorescence complementation, etc. In addition, these methods can also be used to study the interaction sites and mechanisms of action between them.
Knockdown of the NFKBIA gene leads to increased cell growth arrest and apoptosis, which may be related to the aberrant activation of the NF-κB signaling pathway.
The effect on the expression level and activity of molecules related to the NF-κB signaling pathway can be observed by overexpressing or knocking down NFKBIA protein. In addition, studies can also be performed with specific knockout or mutant cell lines.
Its role in physiological and pathological processes can be studied by specifically knocking out the NFKBIA gene using specific short hairpin RNA or zinc finger nuclease technology.
Studies have shown that the expression level of NFKBIA protein is associated with the occurrence and progression of a variety of diseases. For example, in some cancers, the expression levels of the NFKBIA protein are reduced or missing, leading to aberrant activation of the NF-κB signaling pathway.
When cells are stimulated by inflammation, the NFKBIA protein is phosphorylated, causing its dissociation from NF-κB. After dissociation, NF-κB is transferred to the nucleus and activates the transcription of specific genes. In addition, NFKBIA protein can further regulate the activity of NF-κB by interacting with other proteins.
Customer Reviews (3)
Write a reviewI am very happy with the results, they performed very well in my experiments.
It has high sensitivity and strong specificity.
It is easy to use and requires little preparation before the experiment.
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