Recombinant Rat PDE4A Protein, His (Fc)-Avi-tagged

Cat.No. : PDE4A-3990R
Product Overview : Recombinant Rat PDE4A with His (Fc)-Avi tag was expressed and purified
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Source : HEK293
Species : Rat
Tag : His (Fc)-Avi
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥85% by SDS-PAGE
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Storage Buffer : PBS buffer
Gene Name : Pde4a phosphodiesterase 4A, cAMP-specific [ Rattus norvegicus ]
Official Symbol : PDE4A
Gene ID : 25638
mRNA Refseq : NM_013101.3
Protein Refseq : NP_037233.3
UniProt ID : P54748

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Customer Reviews (3)

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    PDE4A requires less storage environment.


      The expression of PDE4A was stable.


        It has the advantage of easy operation in the expression system and can improve the expression efficiency.

        Q&As (6)

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        How effective are PDE4A inhibitors in the treatment of asthma? 04/12/2022

        The inhibitors have been used in the treatment of asthma, and studies have shown that they can significantly reduce the number of asthma attacks and the use of drug D.

        How to introduce the structure of PDE4A? 03/30/2022

        This protein has multiple conserved regions and different subtypes, which is of great significance for the selective inhibition of drugs.

        What is a selective PDE4A inhibitor? 12/25/2021

        Selective PDE4A inhibitors refer to drug molecules that target only the PDE4A protein and do not inhibit other PDE4 homologs.

        What is the mechanism by which PDE4A regulates T cell-mediated autoimmune responses? 05/30/2021

        It plays an important role in the activation and regulation of T cells by regulating cAMP levels, and is involved in T cell-mediated autoimmune responses.

        Are levels of PDE4A associated with sleep disturbances? 02/12/2021

        Studies have shown that PDE4A depletion may be related to sleep-wake behavior and time stress response, but its specific role needs to be further studied.

        What is the expression pattern of PDE4A in T cells? 08/27/2020

        In T cells, PDE4A is mainly expressed in the cytoplasm and peripheral regions of the nuclear membrane.

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