Recombinant Rat PTPN11 Protein

• Cat.No.: PTPN11-4830R
• Product Overview: Recombinant Rat PTPN11 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rat
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Ptpn11 protein tyrosine phosphatase, non-receptor type 11 [ Rattus norvegicus ]
• Official Symbol: PTPN11
• Gene ID: 25622
• mRNA Refseq: NM_001177593.1
• Protein Refseq: NP_001171064.1
• UniProt ID: P41499

Reviews

08/01/2020

Their technical expertise and knowledge of the PTPN11 protein are invaluable resources.

05/18/2016

This reliability reduces experimental variability and enhances the accuracy of data interpretation.

04/11/2016

the manufacturer's commitment to continuous innovation and development of new tools and technologies ensures that I have access to the latest advancements in PTPN11 protein research.

Q&As

Are there genetic tests available to detect PTPN11 mutations?

Yes, genetic testing can identify mutations in the PTPN11 gene, providing valuable information for diagnosis and treatment planning.

How does PTPN11 impact cell signaling pathways?

PTPN11 is involved in various signaling pathways, including the RAS-MAPK pathway, and its mutations can dysregulate these pathways, leading to abnormal cell signaling.

Is PTPN11 involved in normal cellular functions?

Yes, PTPN11 plays a crucial role in normal cellular functions by regulating the activity of proteins through dephosphorylation.

Can PTPN11 be used as a biomarker for certain diseases?

Yes, the presence of PTPN11 mutations can serve as a biomarker for specific cancers and developmental disorders.

How is PTPN11 involved in developmental disorders?

Mutations in PTPN11 can lead to developmental disorders, including Noonan syndrome and LEOPARD syndrome, affecting growth and development.