Recombinant Rhesus Macaque EPHA2 Protein, His (Fc)-Avi-tagged
|Product Overview :||Recombinant Rhesus Macaque EPHA2 with His (Fc)-Avi tag was expressed and purified|
- Gene Information
- Related Products
|Species :||Rhesus Macaque|
|Tag :||His (Fc)-Avi|
|Endotoxin :||< 1.0 EU per μg of the protein as determined by the LAL method|
|Purity :||≥85% by SDS-PAGE|
|Stability :||Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.|
|Storage :||For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.|
|Storage Buffer :||PBS buffer|
|Gene Name :||EPHA2 EPH receptor A2 [ Macaca mulatta (Rhesus monkey) ]|
|Official Symbol :||EPHA2|
|Synonyms :||EPHA2; ephrin type-A receptor 2;|
|Gene ID :||692343|
|mRNA Refseq :||NM_001040678|
|Protein Refseq :||NP_001035768|
|UniProt ID :||Q1HKZ4|
|◆ Recombinant Protein|
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|◆ Assay kits|
|Kit-0326||EphA2 Kinase (Human) Assay/Inhibitor Screening Assay Kit||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
Therapeutic strategies for EPHA2 include inhibition of its expression, blocking its signal transduction pathway, and modulating its interaction with ligands. These strategies may involve the use of small molecule inhibitors, antibodies, or other types of therapeutics.
The expression level of EPHA2 is associated with the occurrence and progression of a variety of diseases. For example, in tumors such as lung, breast, and colorectal cancer, EPHA2 expression levels may be elevated and correlated with the degree of malignancy and poor prognosis of the tumor.
In some tumors, EPHA2 expression levels are associated with poor prognosis in patients. For example, patients with lung cancer who express EPHA2 often have shorter survival. Therefore, the expression level of EPHA2 may be one of the indicators to predict tumor prognosis.
Some diseases can be diagnosed by measuring EPHA2 expression levels, such as immunohistochemistry, western blotting, and real-time PCR.
Yes, EPHA2 can be used as a target for the treatment of certain diseases. For example, inhibition of EPHA2 expression can inhibit tumor growth and spread, so EPHA2 can serve as a potential therapeutic target. In addition, regulating the expression level of EPHA2 may also be helpful in the treatment of diseases such as the nervous system and cardiovascular system.
EPHA2 can promote cancer metastasis and affect the spread and spread of cancer by regulating processes such as invasion and migration of tumor cells. Therefore, inhibition of EPHA2 expression or blocking its signal transduction pathway may have a potential therapeutic effect on inhibiting cancer metastasis.
Customer Reviews (3)Write a review
The protein has low cytotoxicity. -
EPHA2 has good stability, and the test results of heat resistance, acid and alkali resistance and protease degradation resistance are good. -
Kinetic parameters such as enzymatic reaction rate and binding affinity were tested, and the protein performed well. -
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