Recombinant Rhesus Macaque IL22 Protein, His (Fc)-Avi-tagged

• Cat.No.: IL22-2066R
• Product Overview: Recombinant Rhesus Macaque IL22 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rhesus Macaque
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: IL22 interleukin 22 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: IL22
• Synonyms: IL22; interleukin-22
• Gene ID: 718047
• mRNA Refseq: NM_001194724
• Protein Refseq: NP_001181653
• UniProt ID: F6YBU5

Reviews

04/07/2021

High specificity.

03/29/2021

Good for Th17 differentiation.

07/07/2016

Effective in gut repair assays.

Q&As

What is IL22's role in gut epithelial repair?

IL22 enhances gut epithelial repair mechanisms.

What are the downstream targets of IL22 signaling?

IL22 activates STAT3 to modulate downstream targets.

How does IL22 interact with other cytokines in inflammation?

IL22 interacts synergistically with IL-17 during inflammation.

Is IL22 involved in the pathogenesis of autoimmune diseases?

IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.

Does IL22 have a role in metabolic syndrome?

IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.

How is IL22 expression regulated in psoriasis?

IL22 expression is upregulated in psoriasis.

Does IL22 expression change during viral infections?

IL22 expression is upregulated during viral infections like Hepatitis C.

Does IL22 contribute to anti-tumor immunity?

IL22 contributes to anti-tumor immunity by activating NK cells.

How does IL22 modulate T-cell differentiation?

IL22 promotes Th22 cell differentiation.

What impact do IL22 polymorphisms have on its function?

IL22 polymorphisms affect its binding affinity and signaling.