Recombinant Rhesus monkey PTPN1 Protein, His-tagged

• Cat.No.: PTPN1-3704R
• Product Overview: Recombinant Rhesus monkey PTPN1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rhesus monkey
• Tag: His
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: PTPN1 protein tyrosine phosphatase, non-receptor type 1 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: PTPN1
• Synonyms: PTPN1; tyrosine-protein phosphatase non-receptor type 1
• Gene ID: 702016
• mRNA Refseq: NM_001258193
• Protein Refseq: NP_001245122
• UniProt ID: F7B6C1

Reviews

04/06/2023

Timely and precise. Essential for achieving research goals.

08/30/2020

Efficient service, valuable insights. Key to research success.

03/26/2018

Saves time and resources. Critical for our research.

Q&As

What is the impact of altered PTPN1 activity on obesity and related metabolic disorders?

Altered PTPN1 activity is associated with obesity, as it impacts pathways involved in energy balance and fat storage.

How do genetic variations in PTPN1 contribute to metabolic disease susceptibility?

Genetic variations in PTPN1 can affect its activity and thereby influence metabolic processes and disease risk.

What role does PTPN1 play in the development of insulin resistance and type 2 diabetes?

PTPN1 is implicated in insulin resistance, potentially contributing to the development of type 2 diabetes.

How does PTPN1 regulate insulin signaling and glucose metabolism?

It negatively regulates insulin signaling by dephosphorylating insulin receptor substrates, affecting glucose uptake and metabolism.

How does PTPN1 interact with other signaling molecules in regulating metabolic pathways?

PTPN1 interacts with various signaling proteins, playing a role in diverse metabolic pathways including lipid and glucose metabolism.

What is the primary function of PTPN1 in cellular signaling?

PTPN1, also known as Protein Tyrosine Phosphatase Non-Receptor Type 1, is key in dephosphorylating proteins involved in signal transduction.

What potential therapeutic applications could arise from targeting PTPN1 in metabolic diseases?

Targeting PTPN1 could offer therapeutic benefits in treating insulin resistance, type 2 diabetes, and obesity.