Recombinant Swine Chemokine (C-C motif) Ligand 5

• Cat.No.: CCL5-147S
• Product Overview: Recombinant Swine CCL5 protein was expressed inYeastand purified by using Ion-exchange chromatography, 7.9 kDa (68 aa).

Specification

• Species: Pig
• Source: Yeast
• Tag: Non
• Description: CCL5 is an 8kDa protein classified as a chemotactic cytokine or chemokine. CCL5 is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e., IL-2 and IFN-γ) that are released by T cells, CCL5 also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells.
• Sequences Of Amino Acids: SPYASDTTPC CFSYLSRPLP RAHLQEYFYT SSKCSMAAVV FITRKNRQVC ANPEKKWVRE YINTLEMS.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Purification: Ion-exchange chromatography.
• Biological Activity: The biological activity of recombinant swine CCL5 was determined in a chemotaxis assay using a Boyden chamber with freshly isolated swine PBMC monocytes using a Percoll gradient enrichment method. Biological activity typically peaks at 100 ng/mL.
• Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
• Pathways: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; NOD-like receptor signaling pathway; Prion diseases; Toll-like receptor signaling pathway

Gene Information

• Gene Name: CCL5 chemokine (C-C motif) ligand 5 [ Sus scrofa ]
• Synonyms: CCL5; chemokine (C-C motif) ligand 5; RANTES
• Gene ID: 396613
• mRNA Refseq: NM_001129946
• Protein Refseq: NP_001123418