BMP4
-
Official Full Name
bone morphogenetic protein 4
-
Overview
Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. -
Synonyms
BMP4; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP-4; Bone morphogenetic protein 2B; BMP-2B; BMP2B, DVR4; OTTHUMP00000178992;
- Recombinant Proteins
- Cell & Tissue Lysates
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Bovine
- Chicken
- Human
- Mouse
- Pig
- Porcine
- Rabbit
- Rat
- Zebrafish
- CHO-K1
- E. coli
- E.coli
- HEK293
- HeLa
- Human cells
- Mammalian Cell
- Mammalian cells
- Mouse myeloma cell line
- C
- His
- Fc
- GST
- His (Fc)
- Avi
- His(C
- ter)
- Myc
- His|GST
- His|Myc
- His|S
- His|T7
- SUMO
- Met
- N/A
- N
- rFc
- Tag Free
- Involved Pathway
- Protein Function
- Interacting Protein
- BMP4 Related Articles
- BMP4 Related Gene Family
- BMP4 Related Research Area
BMP4 involved in several pathways and played different roles in them. We selected most pathways BMP4 participated on our site, such as Hedgehog signaling pathway, TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Hedgehog signaling pathway | WNT2BA;WNT7B;WNT3;WNT8B;CSNK1G1;ZIC2;SHHB;SHHA;Shh |
TGF-beta signaling pathway | ID4;CHD;ID2B;IFNG1-2;RHOAB;SMAD9;BMP6;BMPR2A;GDF6 |
Hippo signaling pathway | SMAD7;BMP7;CTGF;TEAD2;ITGB2L;LLGL2;FZD3;FZD2;SMAD1 |
Signaling pathways regulating pluripotency of stem cells | MAPK3;PCGF5;WNT1;GRB2;WNT3A;AXIN2;FZD7;SMAD9;LEFTY2 |
Thyroid hormone signaling pathway | THRB;NCOA1;MAPK1;ATP1A2;MED14;HDAC3;THRA;TBC1D4;RXRG |
Pathways in cancer | PRKACG;PDGFRA;CCDC6;TFG;BRCA2;TCEB1;PRKCA;CASP9;PIK3CD |
Basal cell carcinoma | PTCH1;STK36;WNT11;FZD9;WNT9B;WNT5B;WNT7B;FZD5;WNT2B |
BMP4 has several biochemical functions, for example, BMP receptor binding, chemoattractant activity, co-receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP4 itself. We selected most functions BMP4 had, and list some proteins which have the same functions with BMP4. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
BMP receptor binding | BMP7;BMP6;BMP8A;BMP4;BMP7B;BMP2B;BMP7A;PYCARD;BMP3 |
chemoattractant activity | FGF2;VEGFC;SCG2;NTF3;CCL5;HMGB2;PDGFB;MIF;SAA2 |
co-receptor binding | TFR2;NEO1;HFE;BMP2;DKK1;BMP4 |
cytokine activity | Kitl;MSTNB;GM13279;GREM1;IFNPHI4;GDF9;IFNPHI2;INHBA;TGFB3 |
growth factor activity | Fgf15;FGF16;HBEGFB;FGF11A;PDGFC;IL8L2;LEP;EPGN;FGF24 |
heparin binding | THBS1;SERPINE2;COL20A1;AAMP;VEGFAB;ITGAM;KNG1;SELP;FGF4 |
protein binding | RAB27B;POLG2;ARAF;BOLL;Txn1;CCR5;BMP7;ADAM15;CD8B1 |
protein homodimerization activity | CAMK2D;ABCD3;TFAP4;BMP7A;TRIM8;S100A6;BIRC5;GABPB2;GPD1L |
transforming growth factor beta receptor binding | INHBA;BMP8A;GDF9;BMP10;NDR2;SMURF2;GDF1;GDF10B;GDF10 |
BMP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP4.
BMPR1A; FSTL1; WFIKKN2; WFIKKN1; olfml3; chrd; ZFYVE9; C12orf60
- Q&As
- Reviews
Q&As (5)
Ask a questionBMP4 can be used in spinal fusion surgery to stimulate bone growth and fuse vertebrae together, which can alleviate back pain and stabilize the spine.
Mutations in BMP4 or its receptors can lead to congenital disorders, such as orofacial clefts and heart defects.
Yes, there are ongoing trials exploring the use of BMP4 in regenerative medicine for conditions like osteoarthritis and tendon injuries.
Yes, some risks include excessive bone growth, swelling, and inflammation at the application site. These complications can be carefully managed by healthcare providers.
Yes, BMP4 can be used to aid in tissue regeneration in cosmetic procedures, such as in the reconstruction of facial bone defects or enhancement of soft tissue volume.
Customer Reviews (3)
Write a reviewThe BMP4 protein is a valuable resource for researchers due to its high quality and its ability to meet specific experimental needs.
the manufacturer's technical support team can offer prompt assistance in case any issues arise during the handling or application of the BMP4 protein.
The manufacturer's support can play a crucial role in assisting researchers throughout their trials.
Ask a Question for All BMP4 Products
Required fields are marked with *
My Review for All BMP4 Products
Required fields are marked with *