cx3cl1
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  • Official Full Name
  • chemokine (C-X3-C motif) ligand 1
  • Background
  • The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
  • Synonyms
  • CX3CL1; chemokine (C-X3-C motif) ligand 1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin; fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin);
Cat.#:CX3CL1-344CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus Fractalkine Protein, His-tagged
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Cat.#:Cx3cl1-345MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse Cx3cl1 Protein, His-tagged
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Cat.#:CX3CL1-87HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CX3CL1 Protein, His-tagged, Biotinylated
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Cat.#:CX3CL1-926CTag:His
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CX3CL1 Protein (Met1-Gly100), His-tagged
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Cat.#:CX3CL1-2147HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CX3CL1 Protein, GST-tagged
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Cat.#:CX3CL1-4319BTag:N/A
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine CX3CL1 Protein
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Cat.#:Cx3cl1-379MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-X3-C motif) Ligand 1
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Cat.#:Cx3cl1-380MTag:His
Source (Host):S. frugiperdaSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-X3-C motif) Ligand 1, His-tagged
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Cat.#:Cx3cl1-460RTag:N/A
Source (Host):S. frugiperdaSpecies:Rat
Product nameRecombinant Rat Chemokine (C-X3-C motif) Ligand 1
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Cat.#:CX3CL1-223HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human CX3CL1 protein
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Cat.#:CX3CL1-399HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CX3CL1 protein, His-tagged
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Cat.#:CX3CL1-039HTag:N/A
Source (Host):HEK293 cellSpecies:Human
Product nameRecombinant Human CX3CL1 Protein
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Cat.#:CX3CL1-103HTag:Biotin
Source (Host):Species:Human
Product nameHuman CX3CL1, Biotin-tagged
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Cat.#:CX3CL1-114HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human chemokine (C-X3-C motif) ligand 1, His-tagged
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Cat.#:CX3CL1-11712HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CX3CL1, GST-tagged
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Cat.#:CX3CL1-123HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Chemokine (C-X3-C Motif) Ligand 1
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Cat.#:CX3CL1-209HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CX3CL1, Fc-tagged
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Cat.#:CX3CL1-27741THTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human CX3CL1 protein, FLAG-tagged
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Cat.#:CX3CL1-28053THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CX3CL1, His-tagged
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Cat.#:CX3CL1-28060THTag:Fc
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CX3CL1
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Cat.#:CX3CL1-281HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CX3CL1, MIgG2a Fc-tagged
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Cat.#:CX3CL1-286HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CX3CL1, HIgG1 Fc-tagged
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Cat.#:CX3CL1-765HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CX3CL1 protein, His-tagged
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Cat.#:CX3CL1-766HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CX3CL1 protein, His & T7-tagged
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Cat.#:CX3CL1-86HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CX3CL1, His tagged
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Cat.#:Cx3cl1-127MTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-X3-C Motif) Ligand 1
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Cat.#:Cx3cl1-225MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cx3cl1
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Cat.#:CX3CL1-4094MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CX3CL1 Protein
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Cat.#:Cx3cl1-767MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cx3cl1 protein, His-tagged
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Cat.#:Cx3cl1-949MTag:N/A
Source (Host):E.coliSpecies:Mouse
Product nameRecombinant Mouse Cx3cl1 protein
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Cat.#:Cx3cl1-950MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cx3cl1
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Cat.#:Cx3cl1-951MTag:His
Source (Host):Baculovirus Sf21 Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Cx3cl1 Protein, His-tagged
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Cat.#:Cx3cl1-128RTag:N/A
Source (Host):Sf 21 Insect cellsSpecies:Rat
Product nameRecombinant Rat Cx3cl1 Chemokine (C-X3-C Motif) Ligand 1
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Cat.#:CX3CL1-1683RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CX3CL1 Protein
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Cat.#:Cx3cl1-633RTag:N/A
Source (Host):E.coliSpecies:Rat
Product nameRecombinant Rat Cx3cl1 protein
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Cat.#:Cx3cl1-768RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cx3cl1 protein, His-tagged
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Cat.#:Cx3cl1-992RTag:N/A
Source (Host):Baculovirus Sf21 Insect CellsSpecies:Rat
Product nameRecombinant Rat Cx3cl1
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Cat.#:CX3CL1-187CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CX3CL1, Fc-tagged
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Cat.#:CX3CL1-1102RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CX3CL1 Protein, His-tagged
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Cat.#:CX3CL1-176CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CX3CL1, LEVLFQ tagged
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Cat.#:CX3CL1-177CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CX3CL1, Fc tagged
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Cat.#:CX3CL1-3510CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CX3CL1
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Cat.#:CX3CL1-3019HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CX3CL1 cell lysate
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Cat.#:CX3CL1-840CCLTag:N/A
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CX3CL1 cell lysate
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Involved Pathway

CX3CL1 involved in several pathways and played different roles in them. We selected most pathways CX3CL1 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CX3CL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CXCL16; IL6R; CCR8L; GM10591; IL22; IL26; CXCR1; FLT3LG; TNFSF4; BMPR2B
Chemokine signaling pathway
GRK5; GNG12; CCL22; CXCL9; CCL26; CXCL6; CXCL16; ROCK1; XCL2; CCL8
TNF signaling pathway
CXCL1; MAP3K5; DNM1L; CFLAR; MMP14; RELA; TNFAIP3; MAP2K1; CXCL3; IL6

Protein Function

CX3CL1 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CX3CL1 itself. We selected most functions CX3CL1 had, and list some proteins which have the same functions with CX3CL1. You can find most of the proteins on our site.
Function
Related Protein
Function CCR chemokine receptor binding
Related Protein CCRL2; CCL44; CCL34B.4; CCL35.1; CCL22; CCL19A.1; CCL8; CCL19; CCL21; CCL34B.1
Function chemokine activity
Related Protein CKLF; CCL4; CXCL18B; CCL5; CCL3L1; CCL3L3; CCL22; CCL19; C5; Ccl12
Function protein binding
Related Protein FXYD7; STOML2; PCBD1; TNS4; MOAP1; MOXD1; HACL1; SNRPE; NAMPT; SBDS
Function receptor binding
Related Protein Ren1; DHRS4; SLC39A1; CSK; PAOX; PICK1; EFNA1; STRAP; CXCL10; PDGFRB

CX3CL1 Related Articles

Herbst, RS; Soria, JC; et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. NATURE 515:563-+(2014).
Salvador, R; Aridgides, D; et al. Parasite-Derived Neurotrophic Factor/trans-Sialidase of Trypanosoma cruzi Links Neurotrophic Signaling to Cardiac Innate Immune Response. INFECTION AND IMMUNITY 82:3687-3696(2014).

CX3CL1 Related Gene Family

Chemokines Cytokines