dpp4
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  • Official Full Name
  • dipeptidyl-peptidase 4
  • Background
  • The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. [provided by RefSeq, Jul 2008]
  • Synonyms
  • DPP4; dipeptidyl-peptidase 4; CD26; ADABP; ADCP2; DPPIV; TP103; dipeptidyl peptidase 4; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2);
Cat.#:DPP4-116HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human DPP4 Protein, His-tagged
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Cat.#:DPP4-2540HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPP4 Protein, MYC/DDK-tagged
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Cat.#:DPP4-2844HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DPP4 Protein
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Cat.#:DPP4-2845HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DPP4 Protein, GST-tagged
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Cat.#:Dpp4-413MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Dipeptidylpeptidase 4, His-tagged
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Cat.#:DPP4-1081HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPP4, His-tagged
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Cat.#:DPP4-134HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human DPP4
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Cat.#:DPP4-215HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPP4 protein, His-tagged
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Cat.#:DPP4-269HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPP4, Fc tagged
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Cat.#:DPP4-270HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPP4, None tagged
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Cat.#:DPP4-27111THTag:His
Source (Host):High-5 insect cellsSpecies:Human
Product nameRecombinant Human DPP4, His-tagged
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Cat.#:DPP4-27255THTag:His
Source (Host):Species:Human
Product nameRecombinant Human DPP4, His-tagged
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Cat.#:DPP4-3739HTag:N/A
Source (Host):NativeSpecies:Human
Product nameHuman 1PFQ
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Cat.#:DPP4-4760HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human Dipeptidyl-Peptidase 4, His-tagged
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Cat.#:DPP4-7872HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPP4 protein, His-tagged
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Cat.#:DPP4-8313HTag:His
Source (Host):High-5 insect cellsSpecies:Human
Product nameRecombinant Human DPP4, His tagged
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Cat.#:Dpp4-120MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Dpp4, Fc-tagged
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Cat.#:Dpp4-415MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Dpp4 protein, His-tagged
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Cat.#:DPP4-4794MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DPP4 Protein
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Cat.#:Dpp4-7873MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Dpp4 protein, His-tagged
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Cat.#:Dpp4-7874MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Dpp4 protein, His-tagged
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Cat.#:DPP4-1943RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DPP4 Protein
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Cat.#:Dpp4-7875RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Dpp4 protein, His-tagged
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Cat.#:DPP4-119CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DPP4, Fc-tagged
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Cat.#:DPP4-1203CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DPP4 Protein, His-tagged
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Cat.#:DPP4-201CTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DPP4
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Cat.#:DPP4-95CTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DPP4, Fc tagged
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Cat.#:DPP4-1323RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DPP4 Protein, His-tagged
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Cat.#:DPP4-2913CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DPP4
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Cat.#:DPP4-7484ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DPP4
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Cat.#:DPP4-752HTag:N/A
Source (Host):S. frugiperdaSpecies:Human
Product nameRecombinant Human Dipeptidyl-peptidase 4, His-tagged
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Cat.#:DPP4-197HTag:
Source (Host):Species:Human
Product nameNative Human Dipeptidyl Peptidase IV
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Cat.#:DPP4-31HTag:
Source (Host):Species:Human
Product nameNative Human DPP4
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Cat.#:DPP4-2979HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPP4 cell lysate
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Cat.#:DPP4-733CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DPP4 cell lysate
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Cat.#:Kit-0312Tag:
Source (Host):Species:
Product nameDipeptidyl peptidase IV Inhibitor Screening Assay Kit
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Cat.#:Kit-0313Tag:
Source (Host):Species:
Product nameDPP IV Immunocapture Activity Assay Kit
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Cat.#:Kit-0314Tag:
Source (Host):Species:
Product nameDPP4 Activity Fluorometric Assay Kit
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Cat.#:Kit-0315Tag:
Source (Host):Species:
Product nameDPP4 Inhibitor Screening Kit
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Cat.#:Kit-0317Tag:
Source (Host):Species:
Product nameDPPIV/CD26 Assay Kit
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Cat.#:Kit-0316Tag:
Source (Host):Species:
Product nameDPPIV drug discovery Kit
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Involved Pathway

DPP4 involved in several pathways and played different roles in them. We selected most pathways DPP4 participated on our site, such as Incretin synthesis, secretion, and inactivation, Metabolism of proteins, Peptide hormone metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Incretin synthesis, secretion, and inactivation
O3far1; DPP4; GPR119; CDX2; PCSK1; SLC38A8; GPR120; GRP; SPCS3
Metabolism of proteins
SPON1B; MPDU1; MBOAT4; EIF5A; SPON1; TRAPPC6B; DDX11; IGFALS; HYOU1; MUC15
Peptide hormone metabolism
EXOC8; SLC38A8; CGB7; GPR119; ACE; GPR120; DPP4; GZMH; PCSK1; MBOAT4
Protein digestion and absorption
COL4A1; COL13A1; PRSS3; ATP1B2; COL15A1; DPP4; SLC7A7; KCNN4; ATP1B1; KCNQ1
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
O3far1; SLC38A8; GPR119; SPCS3; PCSK1; DPP4; CDX2
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
PCSK1; GPR119; DPP4

Protein Function

DPP4 has several biochemical functions, for example, dipeptidyl-peptidase activity, identical protein binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP4 itself. We selected most functions DPP4 had, and list some proteins which have the same functions with DPP4. You can find most of the proteins on our site.
Function
Related Protein
Function dipeptidyl-peptidase activity
Related Protein DPP8; PRCP; DPP7; FAP; DPEP3; DPP3; DPP4; DPEP2; DPEP1; NAALAD2
Function identical protein binding
Related Protein UHRF1; PDCD6; ALCAMA; AMELX; TRADD; RAD52; TPRG1L; L1CAM; TP73; STXBP1
Function protease binding
Related Protein SELL; TIMP2A; PYCARD; BCL2; HSPA6; RYR1; TNFRSF10A; SERPINB9; MBL1; KIT
Function protein binding
Related Protein RORB; TTC32; RIPK1; SREBF2; IPO5; GBP1; PVRL3; CHRDL2; QKI; PIGK
Function protein homodimerization activity
Related Protein GNPTG; BAX; HAND1; DHDPSL; JAM3; NKX2-5; MYH9; COQ9; Anks6; CPOX
Function receptor binding
Related Protein APOL2; STRAP; NXPH1; ANKRD13C; PLAUR; NRG1; FGF1B; HRG; FGG; GBA
Function serine-type endopeptidase activity
Related Protein MASP1; KLK1B11; HPR; KLK11; PRSS44; PRSS37; KLK12; PCSK9; LONP1; PRSS52
Function serine-type peptidase activity
Related Protein PRSS48; TMPRSS13B; GZMF; RBP3; CMA1; TMPRSS2; ELA2; FURINB; KLK4; TMPRSS11F
Function virus receptor activity
Related Protein CLEC4M; ITGB3; PVR; F11R; SERPINB4; CLDN1; SLC1A5; LDLR; MRC1; CLEC5A

Interacting Protein

DPP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP4.
CXCL11; CXCL10; CXCL2; CCL11; CXCL9

DPP4 Related Articles

Gierer, S; Muller, MA; et al. Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity. JOURNAL OF INFECTIOUS DISEASES 211:889-897(2015).
Tiezzi, F; Parker-Gaddis, KL; et al. A Genome-Wide Association Study for Clinical Mastitis in First Parity US Holstein Cows Using Single-Step Approach and Genomic Matrix Re-Weighting Procedure. PLOS ONE 10:-(2015).