efna1
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  • Official Full Name
  • ephrin-A1
  • Background
  • This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system
  • Synonyms
  • EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis; B61; EFL1; EPLG1; LERK-1; TNFAIP4
Cat.#:EFNA1-1386HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA1 Protein, MYC/DDK-tagged
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Cat.#:EFNA1-3096HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EFNA1 Protein, GST-tagged
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Cat.#:EFNA1-357HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA1 Protein, His-tagged
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Cat.#:EFNA1-1382MTag:Fc/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EFNA1 Protein, Fc/His-tagged
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Cat.#:Efna1-425MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Ephrin A1, His-tagged
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Cat.#:EFNA1-150HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ephrin-A1
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Cat.#:EFNA1-2060HTag:Fc
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human Ephrin-A1, Fc Chimera
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Cat.#:EFNA1-2238HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA1, His tagged
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Cat.#:EFNA1-2326HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA1, Fc-His tagged
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Cat.#:EFNA1-28470THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EFNA1, His-tagged
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Cat.#:EFNA1-28581THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human EFNA1
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Cat.#:EFNA1-355HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA1 Protein, Fc-tagged
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Cat.#:EFNA1-4190HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EFNA1 protein, His-tagged
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Cat.#:Efna1-1730MTag:FC/His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Ephrin A1, Fc-His
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Cat.#:Efna1-3264MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Efna1, Fc tagged
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Cat.#:Efna1-3314MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Efna1, His tagged
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Cat.#:EFNA1-2024RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EFNA1 Protein
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Cat.#:Efna1-7438RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Efna1, His tagged
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Cat.#:EFNA1-1279HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ephrin-A1, His-tagged
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Cat.#:EFNA1-2594HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA1 cell lysate
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Cat.#:EFNA1-2177MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EFNA1 cell lysate
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Cat.#:EFNA1-1514RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat EFNA1 cell lysate
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Involved Pathway

Efna1 involved in several pathways and played different roles in them. We selected most pathways Efna1 participated on our site, such as Arf6 signaling events, Axon guidance, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with Efna1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arf6 signaling events
KIF13B; IPCEF1; GULP1; USP6; AGTR1; FBXO8; ADRB2; EGF; EGFR; ADAP1
Axon guidance
SLC14A2; TRPC4; EPHB4B; FGF20A; SHB; ACTR2; CSNK2A2; MYL12A; EFNA5; EPHB4A
Developmental Biology
EVL; SPTBN1; COL6A1; DNM2; SEMA3AA; RHOB; PLXNC1; JAK1; MEF2AA; DAB2IPB
EPH-Ephrin signaling
ARHGEF28; EFNA3B; ARPC1A; EFNA3; EFNA1A; EFNA5; MYL9; ARPC2; EPHA2; AP2M1
EPH-ephrin mediated repulsion of cells
EPHA2A; EPHB3A; EPHA4A; EPHA10; EFNA1B; EFNB2A; EFNA3; AP2A2; EFNB3B; EFNA3B
EPHA forward signaling
EFNA2; EFNA5; EPHA2; EFNA3; EFNA1; BLK; CRKL; ARHGEF15
EPHA-mediated growth cone collapse
EFNA1; EFNA2; KDR; EPHA2A; EFNA3; EFNA5; EPHA10; MYL12B; EFNA2A; EFNA1A
EPHA2 forward signaling
EFNA1

Protein Function

Efna1 has several biochemical functions, for example, ephrin receptor binding, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Efna1 itself. We selected most functions Efna1 had, and list some proteins which have the same functions with Efna1. You can find most of the proteins on our site.
Function
Related Protein
Function ephrin receptor binding
Related Protein EFNA4; EFNA2; CDK5R1; EFNB2A; CDK5; EFNB2B; EFNA5B; EFNA5; EPHA4; FYN
Function protein binding
Related Protein ASCC3; CACNB2; KHDRBS1; KCNE1L; GEMIN7; HDAC7; SH3RF2; ALS2CR11; PSMB7; NTSR1
Function receptor binding
Related Protein MLYCD; WNT7A; CD86; CADM1A; SRMS; HNF4A; ANGPTL2; FGF1B; NXPH3; ICOSLG

Interacting Protein

Efna1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Efna1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Efna1.
EPHA2; PPBP; XRCC6; EEF1G; SUMO2; KAT5

Efna1 Related Articles

Miao, H; Gale, NW; et al. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. ONCOGENE 34:558-567(2015).
McKinney, N; Yuan, LP; et al. EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. JOURNAL OF NEURO-ONCOLOGY 121:109-118(2015).