Efna1
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Official Full Name
ephrin-A1
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Overview
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system -
Synonyms
EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis; B61; EFL1; EPLG1; LERK-1; TNFAIP4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Human
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- C
- Fc
- hFc
- His
- Fc|His
- GST
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- Efna1 Related Articles
- Efna1 Related Research Area
Efna1 involved in several pathways and played different roles in them. We selected most pathways Efna1 participated on our site, such as Arf6 signaling events, Axon guidance, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with Efna1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Arf6 signaling events | EFNA1;GULP1;IPCEF1;ARAP2;EGFR;ADRB2;ADAP1;KIF13B;AGTR1 |
Axon guidance | JAK2;NRP2;DUSP4;PHB;SIAH2;PTPRA;ROBO1;L1CAM;EGF |
Developmental Biology | RHOC;DLG3;BOC;DPYSL5B;ANK2B;CAP2;EFNA3B;FGF10B;CDK5R1B |
EPH-Ephrin signaling | AP2S1;AP2M1;EFNA1B;EFNB2A;KDR;CLTB;EPHA4A;KALRNB;CFL1 |
EPH-ephrin mediated repulsion of cells | EPHB3A;CLTB;EFNB2A;EFNA1A;AP2B1;EFNA3;EFNB3B;EFNA5;EFNB2 |
EPHA forward signaling | EFNA1;ARHGEF15;EPHA2;CRKL;EFNA3;EFNA2;EFNA5;BLK |
EPHA-mediated growth cone collapse | EPHA10;EFNA1A;MYL9;EPHA4A;KDR;EFNA3B;SHB;EFNA2;EFNA4 |
EPHA2 forward signaling |
Efna1 has several biochemical functions, for example, ephrin receptor binding, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Efna1 itself. We selected most functions Efna1 had, and list some proteins which have the same functions with Efna1. You can find most of the proteins on our site.
Function | Related Protein |
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ephrin receptor binding | EPHA7;EFNA1;EFNB2;EFNA2;ANKS1B;EFNA3;EFNA1B;EFNB2A;FYN |
protein binding | MKNK2;CD9;VBP1;KHDC1B;KREMEN1;ADAMTS10;AP3S1;CRH;CASP6 |
receptor binding | PLG;ABL2;CSNK2B;CCL13;CRTAM;REN;AGRP2;HTT;HACL1 |
Efna1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Efna1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Efna1.
EPHA2; PPBP; XRCC6; EEF1G; SUMO2; KAT5
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.
Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.
EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.
EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.
Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.
Customer Reviews (3)
Write a reviewTheir prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.
This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.
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