TSLP

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TSLP

Official Full Name thymic stromal lymphopoietin
Background This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Alternative splicing of this gene results in two transcript variants.
Synonyms TSLP; Thymic Stromal Lymphopoietin; Thymic stromal lymphopoietin Precursor
    • Species :
    • Cynomolgus
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Mouse
    • NS0
    • Tag :
    • Fc
    • His
    • Avi
    • T7
    • His-Avi
    • LEAF
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TSLP-138H Recombinant Human TSLP Protein, His-tagged, R127A, R130S HEK293 His
    Human TSLP-139H Recombinant Human TSLP Protein, His-tagged, R127A, R130A HEK293 His
    Mouse Tslp-01M Recombinant Mouse Tslp Protein, His-tagged Insect cell His
    Human TSLP-1389H Recombinant Human TSLP Protein, His-tagged HEK293 His
    Human TSLP-1391H Recombinant Human TSLP Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Cynomolgus TSLP-255C Recombinant Cynomolgus TSLP protein, His-tagged HEK293 His
    Human TSLP-371H Recombinant Human TSLP (R127A, R130A) protein, His-tagged HEK293 His
    Human TSLP-372H Recombinant Human TSLP protein, His-tagged HEK293 His
    Human TSLP-391H Recombinant Human TSLP(R127A, R130A) protein, His-Avi-tagged HEK293 His-Avi
    Human TSLP-392H Recombinant Human TSLP protein, His-Avi-tagged HEK293 His-Avi
    Human DMABT-H19273 Mouse Anti-TSLP Monoclonal Antibody Mouse LEAF
    Human TSLP-1390H Recombinant Human TSLP Protein, His-tagged Mammalian cells His
    Human TSLP-2147H Recombinant Human Thymic Stromal Lymphopoietin, Fc Chimera Mammalian Cell Fc
    Human TSLP-312H Recombinant Human TSLP protein E.coli N/A
    Human TSLP-6809H Recombinant Human TSLP protein, His & T7-tagged E.coli His/T7
    Human TSLP-8307H Recombinant Human TSLP N/A
    Mouse TSLP-1742MCL Recombinant Mouse TSLP cell lysate Human Cell N/A
    Mouse Tslp-202M Recombinant Mouse Thymic Stromal Lymphopoietin, His-tagged Insect Cell His
    Mouse Tslp-468M Recombinant Mouse Tslp, His tagged Human Cell His
    Mouse Tslp-469M Recombinant Mouse Tslp protein, FC-tagged HEK293 FC
    Mouse Tslp-6810M Recombinant Mouse Tslp protein, His-tagged E.coli His
    Mouse Tslp-736M Recombinant Mouse Tslp Protein, His-tagged NS0 His
    Rat Tslp-6811R Recombinant Rat Tslp protein, His-tagged E.coli His

    TSLP involved in several pathways and played different roles in them. We selected most pathways TSLP participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSLP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CCL4L1; IL6; CXCR6; LIFRA; KITLGA; PLEKHO2; GM-CSF; Ifna11; IL13RA1; IFNA13
    Jak-STAT signaling pathway BCL2A; SOS1; IL24; AOX1; TYK2; STAT1A; SOCS9; FHL1A; CCND1; PRLRA

    TSLP has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSLP itself. We selected most functions TSLP had, and list some proteins which have the same functions with TSLP. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity GPR19; INHBB; FAM3C; IL4; CMTM3; BMP2; IFNW1; OSTN; GM13288; MSTNA

    TSLP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSLP here. Most of them are supplied by our site. Hope this information will be useful for your research of TSLP.

    PRNP; IKBKG

    McDermott, AJ; Higdon, KE; et al. The role of Gr-1(+) cells and tumour necrosis factor-alpha signalling during Clostridium difficile colitis in mice. IMMUNOLOGY 144:704-716(2015).
    Biedermann, T; Werfel, T; et al. Status quo and prospects for systemic therapy of atopic dermatitis. Biologics ante portas. HAUTARZT 66:108-113(2015).

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