Recombinant Human IL34 Protein, His-tagged

• Cat.No.: IL34-2314H
• Product Overview: Recombinant Human IL34 Protein (Met1-Pro242) with a N-His tag was expressed in E. coli.

Specification

• Description: Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.2 kDa
  Accurate Molecular Mass: 31 kDa
• Protein length: Met1-Pro242
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: IL34 interleukin 34 [ Homo sapiens (human) ]
• Official Symbol: IL34
• Synonyms: IL34; interleukin 34; C16orf77, chromosome 16 open reading frame 77; interleukin-34; IL 34; MGC34647; IL-34; C16orf77
• Gene ID: 146433
• mRNA Refseq: NM_001172771
• Protein Refseq: NP_001166242
• MIM: 612081
• UniProt ID: Q6ZMJ4

Reviews

05/10/2021

IL34 has shown good biocompatibility and safety in related experiments.

01/19/2020

When using IL34 for experiments, the experimental conditions and results are highly repeatable.

10/24/2019

Quality is stable and reliable, with no significant differences between batches.

Q&As

What is the effect of IL34 on tumor prognosis?

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments?

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor?

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing?

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system?

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34?

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.