Description : |
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008] |
Source : |
E. coli |
Species : |
Human |
Tag : |
His(C-ter) |
Form : |
Powder |
Bio-activity : |
Determined by its ability to induce human peripheral blood monocytes (PBMCs) proliferation. The ED50 for this effect is < 30 pg/ml. |
AA Sequence : |
MNEPLEMWPLTQNEECTVTGFLRDK LQYRSRLQYMKHYFPINYKISVPYE GVFRIANVTRLQRAQVSERELRYLW VLVSLSATESVQDVLLEGHPSWKYL QEVETLLLNVQQGLTDVEVSPKVES VLSLLNAPGPNLKLVRPKALLDNCF RVMELLYCSCCKQSSVLNWQDCEVP SPQSCSPEPSLQYAATQLYPPPPWS PSSPPHSTGSVRPVRAQGEGLLP |
Endotoxin : |
Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : |
> 98% (by SDS-PAGE) |
Applications : |
SDS-PAGE |
Notes : |
For laboratory research only, not for drug, diagnostic or other use. |
Storage : |
Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : |
PBS (pH 8.0) |
Reconstitution : |
It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |