Recombinant Active Human IL34 Protein, His-tagged(C-ter)
|Product Overview :||Recombinant Active Human IL34 Protein with His tag (C-ter) was expressed in E. coli.|
- Gene Information
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|Description :||Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]|
|Source :||E. coli|
|Bio-activity :||Determined by its ability to induce human peripheral blood monocytes (PBMCs) proliferation. The ED50 for this effect is < 30 pg/ml.|
|AA Sequence :||MNEPLEMWPLTQNEECTVTGFLRDK LQYRSRLQYMKHYFPINYKISVPYE GVFRIANVTRLQRAQVSERELRYLW VLVSLSATESVQDVLLEGHPSWKYL QEVETLLLNVQQGLTDVEVSPKVES VLSLLNAPGPNLKLVRPKALLDNCF RVMELLYCSCCKQSSVLNWQDCEVP SPQSCSPEPSLQYAATQLYPPPPWS PSSPPHSTGSVRPVRAQGEGLLP|
|Endotoxin :||Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.|
|Purity :||> 98% (by SDS-PAGE)|
|Notes :||For laboratory research only, not for drug, diagnostic or other use.|
|Storage :||Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.|
|Storage Buffer :||PBS (pH 8.0)|
|Reconstitution :||It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.|
|Gene Name :||IL34 interleukin 34 [ Homo sapiens ]|
|Official Symbol :||IL34|
|Synonyms :||IL34; interleukin 34; C16orf77, chromosome 16 open reading frame 77; interleukin-34; IL 34; MGC34647; IL-34; C16orf77;|
|Gene ID :||146433|
|mRNA Refseq :||NM_001172771|
|Protein Refseq :||NP_001166242|
|UniProt ID :||Q6ZMJ4|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
There are no clear studies showing the effect of IL34 on tumor prognosis.
Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.
May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.
No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.
Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.
The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.
Customer Reviews (3)Write a review
IL34 has shown good biocompatibility and safety in related experiments. -
When using IL34 for experiments, the experimental conditions and results are highly repeatable. -
Quality is stable and reliable, with no significant differences between batches. -
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