Acitve Recombinant Mouse CD6 protein(Met1-Gly396), His-tagged
Cat.No. : | CD6-1240M |
Product Overview : | Recombinant extracellular domain of Mouse CD6 (Q91WN5) (Met 1-Gly396) was expressed in HEK293 with a C-terminal polyhistidine tag. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Protein length : | Met1-Gly396 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by the ability of the immobilized protein to support the adhesion of Jurkat Human acute T cell leukemia cells. When 8×10E4 cells/well are added to mCD6-His coated plates (5 μg/mL and 100 μL/well) in the ppresence of 10μg/ml PHA, approximately > 45% cells will adhere specifically after 60 minutes at 37°C. |
Molecular Mass : | The secreted recombinant Mouse CD6 comprises 391 amino acids and has a calculated molecular mass of 42.6 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 60-70 kDa in SDS-PAGE under reducing conditions |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Cd6 CD6 antigen [ Mus musculus ] |
Official Symbol : | CD6 |
Synonyms : | CD6; CD6 antigen; T-cell differentiation antigen CD6; |
Gene ID : | 12511 |
mRNA Refseq : | NM_001037801 |
Protein Refseq : | NP_001032890 |
Products Types
◆ Recombinant Protein | ||
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CD6-1144R | Recombinant Rat CD6 protein(Met1-Asn396), His-tagged | +Inquiry |
CD6-174H | Recombinant Human CD6 Protein, C-His-tagged | +Inquiry |
CD6-1650H | Recombinant Human CD6 protein, His-tagged | +Inquiry |
Cd6-10527M | Recombinant Mouse Cd6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD6-1807MCL | Recombinant Mouse CD6 cell lysate | +Inquiry |
CD6-958RCL | Recombinant Rat CD6 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewFantastic customer support. They genuinely care about the success of our research.
Quality you can trust. Our lab has seen improved precision since using this product.
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Q&As (5)
Ask a questionCD6 provides co-stimulatory signals to T cells, influencing their activation and differentiation. This contributes to the regulation of adaptive immune responses.
CD6 genes exhibit polymorphisms, and certain variations are associated with susceptibility to autoimmune diseases, indicating a potential role in immune dysregulation.
CD6 is involved in immunological synapse formation, and its interactions with ligands, such as ALCAM, play a role in stabilizing T-cell interactions with antigen-presenting cells.
CD6 modulates T-cell trafficking and migration, impacting immune surveillance and inflammation. Its interactions with adhesion molecules contribute to these processes.
CD6 interacts with antigen-presenting cells, facilitating T-cell activation. This interaction is pivotal for the initiation and regulation of immune responses.
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