Active Recombinant Full Length Human CXCL9 Protein

• Cat.No.: CXCL9-33HFL
• Product Overview: Active Recombinant Human CXCL9 Protein (Thr23-Thr125) was expressed in Human embryonic kidney cell.

Specification

• Species: Human
• Source: HEK293
• Protein Length: 23-125 aa
• Description: This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded is thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils.
• Form: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Bio-activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CXCR3. The ED50 for this effect is 0.020-0.300 μg/mL.
• Molecular Mass: 12 kDa
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Upon receipt, store it immediately at the temperature recommended below. Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• N-terminal Sequence Analysis: Thr23
• Reference: 1. Loetscher, M. et al. (1996) J. Exp. Med. 184:963. 2. Liao, F. et al. (1995) J. Exp. Med. 182:1301. 3. Vanguri, P. (1995) J. Neuroimmunol. 56:35.

Gene Information

• Gene Name: CXCL9 chemokine (C-X-C motif) ligand 9 [ Homo sapiens (human) ]
• Official Symbol: CXCL9
• Synonyms: CXCL9; chemokine (C-X-C motif) ligand 9; CMK, MIG, monokine induced by gamma interferon; C-X-C motif chemokine 9; crg 10; Humig; SCYB9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; CMK; MIG; crg-10
• Gene ID: 4283
• mRNA Refseq: NM_002416
• Protein Refseq: NP_002407
• MIM: 601704
• UniProt ID: Q07325