Active Recombinant Human FGF7 Protein

Cat.No. : FGF7-229F
Product Overview : Recombinant Human FGF7 Protein without tag was expressed in CHO.
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Description : Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
Source : CHO
Species : Human
Form : Sterile Filtered White lyophilized (freeze-dried) powder.
Bio-activity : ED50 < 1 ng/mL, measured in a proliferation assay using 4MBr5 cells.
Molecular Mass : 16-18 kDa, observed by reducing SDS-PAGE.
AA Sequence : CNDMTPEQMATNVNCSSPERHTRSY DYMEGGDIRVRRLFCRTQWYLRIDK RGKVKGTQEMKNNYNIMEIRTVAVG IVAIKGVESEFYLAMNKEGKLYAKK ECNEDCNFKELILENHYNTYASAKW THNGGEMFVALNQKGIPVRGKKTKK EQKTAHFLPMAIT
Endotoxin : < 0.2 EU/μg, determined by LAL method.
Purity : > 95% as analyzed by SDS-PAGE and HPLC.
Storage : Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade.
Storage Buffer : Lyophilized after extensive dialysis against PBS.
Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/mL.
Gene Name : FGF7 fibroblast growth factor 7 [ Homo sapiens ]
Official Symbol : FGF7
Synonyms : FGF7; fibroblast growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); keratinocyte growth factor; KGF; FGF-7; heparin-binding growth factor 7; HBGF-7;
Gene ID : 2252
mRNA Refseq : NM_002009
Protein Refseq : NP_002000
MIM : 148180
UniProt ID : P21781

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does FGF7 aid in tissue repair? 11/12/2022

FGF7 stimulates the proliferation and migration of epithelial cells, which are crucial for repairing damaged tissues.

Are there any side effects associated with FGF7 treatment? 05/09/2019

Side effects are generally mild, such as local irritation at the site of application, but comprehensive studies are ongoing.

Can FGF7 be used in regenerative medicine? 06/16/2018

Yes, FGF7 is being explored for its potential in regenerating tissues and promoting healing in various medical fields.

How is FGF7 administered in clinical settings? 08/01/2017

FGF7 can be administered topically or via injection, depending on the specific condition being treated.

Is FGF7 used in dermatology? 02/13/2016

Yes, FGF7 has been investigated for its potential in treating skin disorders, including conditions like psoriasis and atopic dermatitis.

Customer Reviews (3)

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Reviews
03/21/2022

    I highly recommend the FGF7 Protein to fellow researchers seeking a high-quality protein that not only meets their experimental requirements but is also accompanied by exceptional technical support.

    05/01/2021

      The FGF7 Protein's consistent stability and robust performance make it an indispensable tool for studying its multifaceted roles and mechanisms within vital biochemical pathways and cellular processes.

      10/01/2017

        What truly distinguishes the FGF7 Protein is the unparalleled technical support provided by the manufacturer.

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