Active Recombinant Human FLT3LG Protein, His-tagged

Cat.No. : FLT3LG-4374H
Product Overview : Human FLT3LG (156 a.a.) full-length recombinant protein with His tag expressed in Barley grain (Hordeum vulgare).
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Description : Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Source : Barley grain
Species : Human
Tag : His
Form : Lyophilized
Bio-activity : The ED50 in the range of 0.12-0.18 ng/mL, corresponding to specific activity 6.62 X 106 U/mg. We recommend that the optimal concentration for each specific aplication be determined by an initial dose-response assay.
Molecular Mass : 20, 22 kDa
Endotoxin : Endotoxin level is less than 0.005 ng per μg protein (0.05EU/μg) as measured by turbidimetric kinetic assay.
Purity : > 98% by SDS-PAGE
Applications : Western Blot (Recombinant protein)
Functional Study
SDS-PAGE
Storage : Store at -20 centigrade on dry atmosphere.After reconstitution with sterile water to a concentration of no less than 100 ug/mL, store at -20 centigrade. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Aliquot to avoid repeated freezing and thawing.
Concentration : 100 μg/mL
Storage Buffer : Lyophilized from 10 mM acetic acid, pH 5.0
SDS-PAGE: SDS-PAGE Stained with Coomassie Blue
Gene Name : FLT3LG fms-related tyrosine kinase 3 ligand [ Homo sapiens ]
Official Symbol : FLT3LG
Synonyms : FLT3LG; fms-related tyrosine kinase 3 ligand; flt3 ligand; FL; FLT3L;
Gene ID : 2323
mRNA Refseq : NM_001204502
Protein Refseq : NP_001191431
MIM : 600007
UniProt ID : P49771

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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