Active Recombinant Human IL13 Protein
| Cat.No. : | IL13-132H |
| Product Overview : | Recombinant Human IL13 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression. IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive. |
| Source : | E. coli |
| Species : | Human |
| Bio-activity : | TF-1 cell proliferation, ≤5 ng/mL |
| Molecular Mass : | Monomer, 12.6 kDa (115 aa) |
| AA Sequence : | MSPGPVPPSTALRELIEELVNITQN QKAPLCNGSMVWSINLTAGMYCAAL ESLINVSGCSAIEKTQRMLSGFCPH KVSAGQFSSLHVRDTKIEVAQFVKD LLLHLKKLFREGQFN |
| Endotoxin : | ≤1 EUs/μg, Kinetic LAL |
| Purity : | ≥95%, Reducing and Non-Reducing SDS PAGE |
| Stability : | 12 months from date of receipt when stored at -20 to -80 centigrade as supplied. 1 month when stored at 4 centigrade after reconstituting as directed. 3 months when stored at -20 to -80 centigrade after reconstituting as directed. |
| Storage : | Storage Prior to Reconstitution: -20 centigrade |
| Storage Buffer : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium citrate, pH 3.0 |
| Reconstitution : | Sterile 10 mM HCl at 0.1 mg/mL |
| Shipping : | Room temperature |
| Instructions : | Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws. |
| Gene Name : | IL13 interleukin 13 [ Homo sapiens (human) ] |
| Official Symbol : | IL13 |
| Synonyms : | IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13; |
| Gene ID : | 3596 |
| mRNA Refseq : | NM_002188 |
| Protein Refseq : | NP_002179 |
| MIM : | 147683 |
| UniProt ID : | P35225 |
Products Types
| ◆ Recombinant Protein | ||
| IL13-505H | Recombinant Human IL13 Protein | +Inquiry |
| IL13-143H | Recombinant Active Human IL13 Protein, His-tagged(C-ter) | +Inquiry |
| Il13-144M | Recombinant Active Mouse IL13 Protein, His-tagged(C-ter) | +Inquiry |
| IL13-4328Z | Recombinant Zebrafish IL13 Protein | +Inquiry |
| Il13-090M | Active Recombinant Mouse Il13 Protein | +Inquiry |
| ◆ Lysates | ||
| IL13-1894CCL | Recombinant Cynomolgus IL13 cell lysate | +Inquiry |
| IL13-1336MCL | Recombinant Mouse IL13 cell lysate | +Inquiry |
| IL13-001HCL | Recombinant Human IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a question
How does flow cytometry help quantify IL13 receptor expression on different cell populations?
12/29/2022
Flow cytometry quantifies IL13 receptor expression on cells.
What are the benefits of using transgenic animal models to study IL13's in vivo functions?
07/05/2022
Transgenic models illuminate IL13's in vivo functions.
Could you explain the role of ELISA in quantifying IL13 secretion levels in cell cultures?
02/23/2022
ELISA quantifies IL13 secretion in cell cultures accurately.
How can siRNA knockdown experiments reveal IL13's effects on specific cellular processes?
06/13/2021
siRNA knockdown uncovers IL13's specific cellular effects.
How does co-immunoprecipitation identify interacting partners in IL13-mediated signaling complexes?
07/28/2019
Co-immunoprecipitation identifies IL13 signaling partners.
What techniques can differentiate IL13-mediated signaling pathways from IL4 pathways?
07/23/2019
Differential techniques distinguish IL13 and IL4 signaling pathways.
Could you elaborate on the use of reporter gene assays to assess IL13-driven transcriptional activity?
12/16/2018
Reporter gene assays gauge IL13-driven transcription.
Can you describe the applications of microarray analysis in profiling IL13-induced gene expression changes?
11/14/2018
Microarray analysis profiles IL13-induced gene expression.
What experimental methods determine the impact of IL13 on tissue remodeling processes?
08/04/2018
Experimental methods reveal IL13's impact on tissue remodeling.
How does site-directed mutagenesis help identify critical residues in IL13 receptor binding?
07/04/2018
Site-directed mutagenesis identifies key residues in IL13 receptor binding.
Customer Reviews (3)
Write a reviewReviews
11/29/2021
Effective in Th2 cell differentiation. -
04/22/2020
Good for cytokine assays. -
01/26/2019
High yield in expression. -
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