| Cat.No. : |
CCL22-3861M
Optional Service: Optional requirements on this protein
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| Product Overview : |
The extracellular domain of mouse CCL22 (NP_033163.1)(Gly25-Ser92) is fused to the N-terminus of the Fc portion of a mutant mouse IgG2a was expressed in CHO cell. |
| Description : |
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are afamily of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines areproteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activityfor monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It alsodisplays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils,eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokinemay play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects ofactivated T lymphocyte physiology. |
| Source : |
CHO cell |
| Species : |
Mouse |
| Tag : |
MIgG2a Fc-tagged, mutant |
| Form : |
Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : |
Measured by a chemotaxis bioassay using human activated lymphocytes |
| Molecular Mass : |
34 KDa |
| AA Sequence : |
Gly25-Ser92 |
| Endotoxin : |
<0.06 eu/μg as determined by lal test.> |
| Purity : |
≥98%, by SDS-PAGE under reducing conditions. |
| Stability : |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : |
Reconstitute at 100μg/ml in sterile PBS. |
| Warning : |
Avoid freeze/thaw cycles. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
