Active Recombinant Mouse Tigit, Fc Chimera

• Cat.No.: Tigit-693M
• Product Overview: Recombinant Mouse Tigit (Accession # NP_001139797) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: Gly26
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Mouse CD155/PVR is coated at 2.5 µg/mL (100 µL/well), the concentration of Recombinant Mouse TIGIT Fc Chimera that produces 50% optimal binding response is typically 10-50 ng/mL.
• Molecular Mass: Recombinant Mouse Tigit, Fc Chimera has a calculated MW of 40.1 kDa (monomer). In SDS-PAGE migrates as 50-60 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Tigit T cell immunoreceptor with Ig and ITIM domains [ Mus musculus ]
• Official Symbol: Tigit
• Synonyms: TIGIT; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; Vstm3; ENSMUSG00000071552
• Gene ID: 100043314
• mRNA Refseq: NM_001146325
• Protein Refseq: NP_001139797