Recombinant Human AKR1B10, His-tagged
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| Cat. No. : | AKR1B10-2764H |
| Product Overview : | Recombinant human ARL1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. |
| Description : | ADP-ribosylation factor-like protein 1(ARL1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. |
| Source : | E.coli. |
| Purity : | > 95% by SDS – PAGE. |
| Sequences : | MGSSHHHHHH SSGLVPRGSH MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q. |
| Molecular Weight : | 22.5kDa (201aa)confirmed by MALDI-TOF. |
| Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 100mM NaCl, 2mM DTT. |
| Concentration : | 0.25mg/ml (determined by Bradford assay). |
| Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| PDB rendering based on 1zua. : |
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| Gene Name : | AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) [ Homo sapiens ] |
| Synonyms : | AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase); HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12; MGC14103; AKR1B10; EC 1.1.1.2; Aldo-keto reductase family 1 member B10; ARP; EC 1.1.1.-; ARP; aldo-keto reduct ase family 1, member B10; aldose reductase-like 1; small intestine reductase; aldose reductase-like peptide; aldose reductase-related protein; aldo-keto reductase family 1, member B11 (aldose reductase-like); Aldose reductase-like; SI reductase |
| Gene ID : | 57016 |
| mRNA Refseq : | NM_020299 |
| Protein Refseq : | NP_064695 |
| MIM : | 604707 |
| UniProt ID : | O60218 |
| Chromosome Location : | 7q33 |
| Pathway : | Ascorbate and aldarate metabolism; Bile acid biosynthesis; Bisphenol A degradation; Butanoate metabolism; Fructose and mannose metabolism; Galactose metabolism; Glycine, serine and threonine metabolism; Linoleic acid metabolism; Lysine degradation; Nucleotide sugars metabolism; Tetrachloroethene degradation |
| Function : | aldo-keto reductase activity; oxidoreductase activity; protein binding |
◆ Recombinant Protein
| AKR1B10-6197C | Recombinant Chicken AKR1B10 | +Inquiry |
| AKR1B10-410H | Recombinant Human AKR1B10 Protein, GST-tagged | +Inquiry |
| AKR1B10-1533H | Recombinant Human AKR1B10 protein, His & T7-tagged | +Inquiry |
| AKR1B10-406H | Recombinant Human AKR1B10 protein | +Inquiry |
| AKR1B10-995H | Recombinant Human AKR1B10 Protein, Met & His-tagged | +Inquiry |
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◆ Lysates
| AKR1B10-8931HCL | Recombinant Human AKR1B10 293 Cell Lysate | +Inquiry |
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AKR1A1AKR1B1AKR1B10AKR1C1AKR1C3AKR1D1AKR7A2AKR7A3AKR1C4AKR1C2AKR1E2Akr1b3Akr1b7Akr1b8Akr1c12Akr1c12l1Akr1c13Akr1c14Akr1c18Akr1c19Akr1c20Akr1c21Akr1c6Akr1clAkr1e1Akr7a5AKR1B15
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