Recombinant Human Interleukin 28 Receptor, Alpha (interferon, lambda receptor)
Cat.No. : | IL28RA-601H |
Product Overview : | Recombinant HumanIFN-lambda 2 contains 175 amino acid residues. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL28RA-601H |
Description : | IL28RA is a subunitfor the interleukin-28 receptor. IL28RA is its human gene. The proteinencoded by this gene belongs to the class II cytokine receptor family. Thisprotein forms a receptor complex with interleukine 10 receptor, beta(IL10RB). The receptor complex has been shown to interact with three closelyrelated cytokines, including interleukin 28A (IL28A), interleukin 28B(IL28B), and interleukin 29 (IL29). The expression of all three cytokines canbe induced by viral infection. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized withoutadditives |
Purity : | > 95% asdetermined by SDS-PAGE and HPLC analysis. |
Molecular Weight : | 19.8 kDa |
Endotoxin Level : | < 0.1 ng/μg ofIFN-lambda 2 |
Biological Activity : | Determined by itsability to activate STAT following receptor-ligand interaction. |
Reconstitution : | Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. |
Storage : | Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C.Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | IL28RA |
Pathways : | Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway |
Gene Name : | IL28RA interleukin 28receptor, alpha (interferon, lambda receptor) [ Homo sapiens ] |
Synonyms : | IL28RA; interleukin28 receptor, alpha (interferon, lambda receptor); IFNLR; LICR2; IFNLR1;CRF2/12; IL-28R1; interleukin-28 receptor subunit alpha; CRF2-12;IL-28RA; IL-28R-alpha; IFN-lambda-R1; OTTHUMP00000003067; OTTHUMP00000003068;OTTHUMP00000003069; OTTHUMP00000003070; IFN-lambda receptor 1; interleukin 28receptor A; IL-28 receptor subunit alpha; interferon lambda receptor 1;interferon lambda, receptor 1; class II cytokine receptor CRF2/12;interleukin or cytokine receptor 2; cytokine receptor class-II member 12;cytokine receptor family 2 member 12; likely interleukin or cytokine receptor2; Interleukin-28receptor subunit alpha; Cytokinereceptor class-II member 12; Cytokine receptor family 2 member 12; Interferonlambda receptor 1; Likely interleukin or cytokine receptor 2 |
Gene ID : | 163702 |
mRNA Refseq : | NM_170743 |
Protein Refseq : | NP_734464 |
MIM : | 607404 |
UniProt ID : | Q8IU57 |
Chromosome Location : | 1p36.11 |
Function : | contributes tocytokine receptor activity; protein binding; receptor activity |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIL-28RA can treat hepatitis B virus infection and is also used in the development of chronic hepatitis B.
IL-28RA can enhance the body's immune function, thereby inhibiting the growth and reproduction of pathogens.
At normal doses, IL-28RA has no significant adverse effects on humans.
Recombinant IL-28RA can effectively treat hepatitis B without causing significant side effects.
IL-28RA is suitable for clinical use and has been used in many medical facilities.
This protein can improve the body's resistance to disease.
Customer Reviews (3)
Write a reviewSmall harm to the human body, high safety.
The detection method is very sensitive and can be detected in small quantities.
It is very stable and does not denature even at low temperatures.
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