Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Interleukin 28 Receptor, Alpha (interferon, lambda receptor)

Cat.No. : IL28RA-601H
Product Overview : Recombinant HumanIFN-lambda 2 contains 175 amino acid residues.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : IL28RA-601H
Description : IL28RA is a subunitfor the interleukin-28 receptor. IL28RA is its human gene. The proteinencoded by this gene belongs to the class II cytokine receptor family. Thisprotein forms a receptor complex with interleukine 10 receptor, beta(IL10RB). The receptor complex has been shown to interact with three closelyrelated cytokines, including interleukin 28A (IL28A), interleukin 28B(IL28B), and interleukin 29 (IL29). The expression of all three cytokines canbe induced by viral infection.
Source : E. coli
Species : Human
Form : Lyophilized withoutadditives
Purity : > 95% asdetermined by SDS-PAGE and HPLC analysis.
Molecular Weight : 19.8 kDa
Endotoxin Level : < 0.1 ng/μg ofIFN-lambda 2
Biological Activity : Determined by itsability to activate STAT following receptor-ligand interaction.
Reconstitution : Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions.
Storage : Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C.Avoid repeated freeze-thaw cycles.
OfficialSymbol : IL28RA
Pathways : Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway
Gene Name : IL28RA interleukin 28receptor, alpha (interferon, lambda receptor) [ Homo sapiens ]
Synonyms : IL28RA; interleukin28 receptor, alpha (interferon, lambda receptor); IFNLR; LICR2; IFNLR1;CRF2/12; IL-28R1; interleukin-28 receptor subunit alpha; CRF2-12;IL-28RA; IL-28R-alpha; IFN-lambda-R1; OTTHUMP00000003067; OTTHUMP00000003068;OTTHUMP00000003069; OTTHUMP00000003070; IFN-lambda receptor 1; interleukin 28receptor A; IL-28 receptor subunit alpha; interferon lambda receptor 1;interferon lambda, receptor 1; class II cytokine receptor CRF2/12;interleukin or cytokine receptor 2; cytokine receptor class-II member 12;cytokine receptor family 2 member 12; likely interleukin or cytokine receptor2; Interleukin-28receptor subunit alpha; Cytokinereceptor class-II member 12; Cytokine receptor family 2 member 12; Interferonlambda receptor 1; Likely interleukin or cytokine receptor 2
Gene ID : 163702
mRNA Refseq : NM_170743
Protein Refseq : NP_734464
MIM : 607404
UniProt ID : Q8IU57
Chromosome Location : 1p36.11
Function : contributes tocytokine receptor activity; protein binding; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Which types of hepatitis B can IL-28RA be treated? 11/12/2022

IL-28RA can treat hepatitis B virus infection and is also used in the development of chronic hepatitis B.

What is the action mechanism of IL-28RA in vivo? 06/22/2022

IL-28RA can enhance the body's immune function, thereby inhibiting the growth and reproduction of pathogens.

Does IL-28RA have an effect on human body? 07/14/2021

At normal doses, IL-28RA has no significant adverse effects on humans.

IL-28ra in a role in the treatment of hepatitis b is what? 03/19/2021

Recombinant IL-28RA can effectively treat hepatitis B without causing significant side effects.

Is IL-28RA suitable for clinical treatment? 07/16/2020

IL-28RA is suitable for clinical use and has been used in many medical facilities.

Can IL-28RA improve the body's resistance to disease? 01/14/2019

This protein can improve the body's resistance to disease.

Customer Reviews (3)

Write a review
Reviews
10/04/2020

    Small harm to the human body, high safety.

    08/08/2020

      The detection method is very sensitive and can be detected in small quantities.

      01/14/2019

        It is very stable and does not denature even at low temperatures.

        Ask a Question for All IL28RA Products

        Required fields are marked with *

        My Review for All IL28RA Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends