Native Human Alkaline Phosphatase

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Native Human Alkaline Phosphatase

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Cat.No. : ALPL-5324H
Product Overview : Native human ALPL was purified from Human Liver.
Description : Alkaline Phosphatase (ALP) is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. In humans, alkaline phosphatase is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. The optimal pH for the enzyme activity is pH=10 in standard conditions.
Source : Human Liver
Species : Human
Form : Ammonium Sulfate Suspension
Bio-activity : >25 U/mL
Unit Definition : One unit will convert one micromole of p-nitrophenyl phosphate to p-nitrophenol and phosphate per minute at 37C in the presence of AMP (2-amino-2-methyl-1-propanol) at pH 10.35
Storage : 2-8 °C
Concentration : Typically >5 mg protein/mL
Gene Name : ALPL alkaline phosphatase, liver/bone/kidney [ Homo sapiens ]
Official Symbol : ALPL
Synonyms : ALPL; alkaline phosphatase, liver/bone/kidney; HOPS; alkaline phosphatase, tissue-nonspecific isozyme; TNSALP; glycerophosphatase; tissue-nonspecific ALP; alkaline phosphomonoesterase; liver/bone/kidney-type alkaline phosphatase; alkaline phosphatase live
Gene ID : 249
mRNA Refseq : NM_000478
Protein Refseq : NP_000469
MIM : 171760
UniProt ID : P05186
Chromosome Location : 1p36.12
Pathway : Endochondral Ossification, organism-specific biosystem; Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : alkaline phosphatase activity; hydrolase activity; metal ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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