Recombinant Human Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric
Cat.No. : | MYL12A-5458H |
Product Overview : | Recombinant Human MYL12A is produced in E. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MYL12A-5458H |
Description : | MYL12A is required for cytokinesis at the end of celldivision, when a contractile ring near the plasmalemma divides the cytoplasmof the daughter cells. They are involved in cytoplasmic streaming movementsin tissues, and especially in activation of motile cells such as fibroblastsand macrophages. Activation of non-muscle myosin-II is achieved byphosphorylation of Ser33 in the motif KKRPQRATSN by a dedicated, Ca +2Calmodulin regulated light chain kinase (MLCK). |
Source : | E. coli |
Species : | Human |
Form : | Sterile filteredliquid in 20 mM HEPES-KOH, pH 7.0 + 50 mM NaCl + 1 mM EDTA + 1 mM DTT. |
Concentration : | 0.5 mg/mL |
storage : | Stablefor 1 year in working aliquots at -20°C to -80°C. Avoid repeated freeze-thawcycles. |
OfficialSymbol : | MYL12A |
Pathways : | Focal adhesion; Focal adhesion;Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Tightjunction |
Gene Name : | MYL12A myosin, light chain 12A,regulatory, non-sarcomeric [ Homo sapiens ] |
Synonyms : | MYL12A; myosin, light chain12A, regulatory, non-sarcomeric; MLCB; MRCL3; MRLC3; MYL2B; myosin regulatorylight chain 12A; MLC-2B; myosin RLC; OTTHUMP00000162243; myosin regulatorylight chain 3; myosin regulatory light chain MRCL3; myosin regulatory lightchain MRLC3; myosin regulatory light chain 2, nonsarcomeric; myosin, lightpolypeptide, regulatory, non-sarcomeric (20kD); RLC |
Gene ID : | 10627 |
mRNA Refseq : | NM_006471 |
Protein Refseq : | NP_006462 |
UniProt ID : | P19105 |
Chromosome Location : | 18p11.31 |
Function : | calcium ion binding; glutamatereceptor binding |
Products Types
◆ Recombinant Protein | ||
MYL12A-2740R | Recombinant Rhesus Macaque MYL12A Protein, His (Fc)-Avi-tagged | +Inquiry |
MYL12A-5536H | Recombinant Human MYL12A Protein, His-tagged | +Inquiry |
MYL12A-3511R | Recombinant Rat MYL12A Protein, His (Fc)-Avi-tagged | +Inquiry |
MYL12A-3606H | Recombinant Human MYL12A, His-tagged | +Inquiry |
MYL12A-6893C | Recombinant Chicken MYL12A | +Inquiry |
◆ Lysates | ||
MYL12A-4030HCL | Recombinant Human MYL12A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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