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Recombinant Mouse Interleukin 1 Family, Member 9

Cat. No.: Il1f9-648M
Product Overview: RecombinantMouse Il1f9 protein was expressed in E. coli. Gly13-Ser164.
Description: Il1f9 is amember of the IL-1 family which includes IL-1β, IL-1α, IL-1ra, IL-18, IL-36Ra(IL-1F5), IL-36α (IL-1F6), IL-36β (IL-1F8), IL-37 (IL-1F7) and IL-1F10. Allfamily members show a 12 β-strand, β-trefoil configuration, and are believedto have arisen from a common ancestral gene. Mouse Il1f9 is an 18-22kDa, 164 amino acid (aa) intracellular and secreted protein that contains nosignal sequence, no prosegment and no potential N-linked glycosylation sites.Mouse Il1f9 (aa 13-64)shares 58%, 84%, 64% and 60% aa sequence identity with human, rat, equine andbovine Il1f9, respectively,and 23-57% aa sequence identity with other family members.
Source: E. coli
Form: Lyophilizedfrom a 0.2 um filtered solution in MOPS, NaCl, TCEP and EDTA with BSA as acarrier protein.
N-terminalSequence: Gly13
MolecularWeight: 17.3 kDa
Activity: Measuredby its ability to induce IL-6 secretion by NIH/3T3 mouse embryonic fibroblasts.The ED50 for this effect is typically 3-18 ng/mL.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 17 kDa,reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstituteat 100μg/mL in PBS containing at least 0.1% human or bovine serum albumin.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to --70°C assupplied. 1 month, 2 to 8°C under sterile conditions afterreconstitution. 3 months, -20 to -70°C under sterile conditions afterreconstitution.
Gene Name: Il1f9 interleukin 1 family,member 9 [ Mus musculus ]
Official Symbol: Il1f9
Synonyms: Il1f9; interleukin 1family, member 9; Il36g; interleukin-36 gamma; IL-1F9; interleukin-1family member 9
Gene ID: 215257
mRNA Refseq: NM_153511
Protein Refseq: NP_705731
UniProt ID: Q3U0P4
Chromosome Location: 2
Function: cytokine activity;molecular_function

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