|Product Overview:||Recombinant human LOX containinggst tag with the vector PGEX-4T was expressed in E.coli.|
|Description:||The protein encoded by this gene is anextracellular copper enzyme that initiates the crosslinking of collagens andelastin. The enzyme catalyzes oxidative deamination of the epsilon-aminogroup in certain lysine and hydroxylysine residues of collagens and lysineresidues of elastin. In addition to crosslinking extracellular matrixproteins, the encoded protein may have a role in tumor suppression. Defectsin this gene are a cause of autosomal recessive cutis laxa type I (CL typeI). Two transcript variants encoding different isoforms have been found forthis gene.|
|Antigen peptide region:||1-417aa|
|Storage Buffer:||1M PBS (58 mM Na2HPO4,17 mM NaH2PO4,68 mM NaCl, pH8.) added with 100 mM GSH and 1% Triton X-100,15%glycerol.|
|Gene Name:||LOX lysyl oxidase [ Homo sapiens]|
|Synonyms:||LOX;lysyl oxidase; MGC105112;protein-lysine6-oxidase; EC 18.104.22.168; OTTHUMP00000159161|
|Function:||copperion binding; metal ion binding; oxidoreductase activity|
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