"LOX" Related Products

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Recombinant Human LOX, GST-tagged

Cat. No.: LOX-90H
Product Overview: Recombinant human LOX containinggst tag with the vector PGEX-4T was expressed in E.coli.
Description: The protein encoded by this gene is anextracellular copper enzyme that initiates the crosslinking of collagens andelastin. The enzyme catalyzes oxidative deamination of the epsilon-aminogroup in certain lysine and hydroxylysine residues of collagens and lysineresidues of elastin. In addition to crosslinking extracellular matrixproteins, the encoded protein may have a role in tumor suppression. Defectsin this gene are a cause of autosomal recessive cutis laxa type I (CL typeI). Two transcript variants encoding different isoforms have been found forthis gene.
Source: E.coli
Species: Human
Antigen peptide region: 1-417aa
Storage Buffer: 1M PBS (58 mM Na2HPO4,17 mM NaH2PO4,68 mM NaCl, pH8.) added with 100 mM GSH and 1% Triton X-100,15%glycerol.
OfficialSymbol: LOX
Gene Name: LOX lysyl oxidase [ Homo sapiens]
Synonyms: LOX;lysyl oxidase; MGC105112;protein-lysine6-oxidase; EC 1.4.3.13; OTTHUMP00000159161
Gene ID: 4015
mRNA Refseq: NM_001178102
Protein Refseq: NP_001171573
MIM: 153455
UniProt ID: P28300
Chromosome Location: 5q23.2
Function: copperion binding; metal ion binding; oxidoreductase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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