Recombinant Human Platelet Derived Growth Factor D, His-tagged

• Cat.No.: PDGFD-7140H
• Product Overview: Recombinant human PDGFD protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 16.6 kDa.

Specification

• Description: Platelet-derived growth factor D, also known as PDGFD, plays an important role in wound healing. This protein induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. This protein can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol.
• Molecular Mass: 16.6 kDa (146aa)
• Protein length: 250-370aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSYHDR KSKVDLDRLN DDAKRYSCTP RNYSVNIREE LKLANVVFFP RCLLVQRCGG NCGCGTVNWR SCTCNSGKTV KKYHEVLQFE PGHIKRRGRA KTMALVDIQL DHHERCDCIC SSRPPR
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PDGFD platelet derived growth factor D [ Homo sapiens ]
• Official Symbol: PDGFD
• Synonyms: PDGFD; platelet derived growth factor D; platelet-derived growth factor D; IEGF; MSTP036; SCDGF B; spinal cord derived growth factor B; PDGF-D; iris-expressed growth factor; spinal cord-derived growth factor B; spinal cord-derived growth factor-B; SCDGFB; SCDGF-B; MGC26867
• Gene ID: 80310
• mRNA Refseq: NM_025208
• Protein Refseq: NP_079484
• MIM: 609673
• UniProt ID: Q9GZP0
• Chromosome Location: 11q22.3
• Pathway: Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem
• Function: growth factor activity